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[口咽癌的病因病理学与预防]

[Aetiopathology and prevention of oropharyngeal cancer].

作者信息

Chimenos-Küstner E, Marques-Soares M S, Schemel-Suárez M

机构信息

Departamento de Odontoestomatología, Facultad de Medicina y Ciencias de la Salud, Universidad de Barcelona, Barcelona, España.

Departamento de Clínica y Odontología Social, Universidad Federal de Paraíba, João Pessoa, Paraíba, Brasil.

出版信息

Semergen. 2019 Oct;45(7):497-503. doi: 10.1016/j.semerg.2019.03.004. Epub 2019 May 10.

DOI:10.1016/j.semerg.2019.03.004
PMID:31079896
Abstract

Oropharyngeal cancer is in the sixth position of cancer incidence in the world (after colorectal, breast, prostate, bladder, and cervix uteri cancer). More than 90% of them are squamous cell carcinoma. This type of cancer can originate on the lip, oral cavity, pharynx, and larynx. The risk factors associated with oropharyngeal cancer are tobacco, alcohol, and poor oral hygiene. However, other conditions, such as infection with human papilloma virus (HPV) and oral dysbiosis, are gaining prominence. Pre-malignant and malignant lesions are related to diverse factors that can be monitored by the health professional. These professionals are also in an ideal position to influence and advise patients on healthy life habits that contribute to prevent or treat metabolic-endocrine syndromes associated with the development of pre-cancerous disease and cancer located in different organs.

摘要

口咽癌在全球癌症发病率中位列第六(仅次于结直肠癌、乳腺癌、前列腺癌、膀胱癌和子宫颈癌)。其中超过90%为鳞状细胞癌。这类癌症可起源于唇部、口腔、咽部和喉部。与口咽癌相关的风险因素包括烟草、酒精和不良口腔卫生习惯。然而,其他情况,如人乳头瘤病毒(HPV)感染和口腔生态失调,正日益受到关注。癌前病变和恶性病变与多种因素有关,健康专业人员可以对这些因素进行监测。这些专业人员也处于理想位置,能够就有助于预防或治疗与癌前疾病和不同器官癌症发展相关的代谢 - 内分泌综合征的健康生活习惯向患者提供影响和建议。

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