Laboratory for Bio-feed and Molecular Nutrition, College of Animal Science and Technology, Southwest University, Chongqing 400715, China.
Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Curr Protein Pept Sci. 2019;20(7):674-682. doi: 10.2174/1389203720666190514120023.
Intestines are not only major organs for nutrient digestion and absorption, but are also the largest immune organ in pigs. They are essential for maintaining the health and growth of piglets. Fatty acids, including short-chain fatty acids, medium-chain fatty acids, and long-chain polyunsaturated fatty acids, are important nutrients; they are a major energy source, important components of the cell membrane, metabolic substrates in many biochemical pathways, cell-signaling molecules, and play role as immune modulators. Research has shown that fatty acids exert beneficial effects on intestinal health in animal models and clinical trials. The objective of this review is to give a clear understanding of the regulatory effects of fatty acids of different chain lengths on intestinal health in pigs and their signaling pathways, providing scientific reference for developing a feeding technique to apply fatty acids to piglet diets.
肠道不仅是营养消化和吸收的主要器官，也是猪体内最大的免疫器官。它对于仔猪的健康和生长至关重要。脂肪酸，包括短链脂肪酸、中链脂肪酸和长链多不饱和脂肪酸，是重要的营养物质；它们是主要的能量来源、细胞膜的重要组成部分、许多生化途径中的代谢底物、细胞信号分子，并作为免疫调节剂发挥作用。研究表明，脂肪酸在动物模型和临床试验中对肠道健康有有益影响。本综述的目的是清楚地了解不同链长的脂肪酸对猪肠道健康的调节作用及其信号通路，为开发将脂肪酸应用于仔猪日粮的饲养技术提供科学参考。
