Stegink L D, Andersen D W, Zike W L
JPEN J Parenter Enteral Nutr. 1987 Mar-Apr;11(2):124-8. doi: 10.1177/0148607187011002124.
Oligosaccharides are potential sources of carbohydrate-derived energy for use in parenteral nutrition regimens. Clinical studies indicate that although some patients utilize infused oligosaccharides well, many patients do not. These results suggest that oligosaccharides might be useful as a parenteral energy source for selected patients. This report describes a method, suitable for use by nursing staff on the ward, to determine oligosaccharide utilization and identify patients utilizing oligosaccharides well. Oligosaccharides excreted in urine are hydrolyzed enymatically to glucose using alpha-glucosidase and alpha-amylase, and the glucose released is measured by a test tape method. The results obtained agree well with the acid hydrolysis-spectrophotometric assay for oligosaccharide excretion used in earlier studies. The method readily identified postsurgical patients utilizing infused oligosaccharides poorly in both prospective and retrospective studies.
低聚糖是肠外营养方案中碳水化合物衍生能量的潜在来源。临床研究表明，虽然一些患者能很好地利用输注的低聚糖，但许多患者却不能。这些结果表明，低聚糖可能对特定患者作为肠外能量来源有用。本报告描述了一种适合病房护理人员使用的方法，用于确定低聚糖的利用率并识别能很好利用低聚糖的患者。使用α-葡萄糖苷酶和α-淀粉酶将尿液中排泄的低聚糖酶解为葡萄糖，释放的葡萄糖通过试纸法进行测量。所获得的结果与早期研究中用于低聚糖排泄的酸水解-分光光度法测定结果非常吻合。在前瞻性和回顾性研究中，该方法都能很容易地识别出术后对输注低聚糖利用不佳的患者。
