Department of General Practice and Elderly Care Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Department of Pulmonary Diseases and Tuberculosis, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Eur J Cancer Care (Engl). 2019 May;28(3):e13086. doi: 10.1111/ecc.13086. Epub 2019 May 14.
Symptoms of depression, anxiety and distress are common in the first years after a cancer diagnosis, but little is known about the prevalence of these symptoms at the long term. The aim of this review was to describe the prevalence of symptoms of depression, anxiety and distress in long-term cancer survivors, five or more years after diagnosis, and to provide implications for primary care.
We performed a systematic literature search in the PubMed, PsycINFO and CINAHL databases. Studies were eligible when reporting on the prevalence of symptoms of depression, anxiety and/or distress in long-term cancer survivors (≥5 years after diagnosis), treated with curative intent.
A total of 20 studies were included. The reported prevalence of depressive symptoms (N = 18) varied from 5.4% to 49.0% (pooled prevalence: 21.0%). For anxiety (N = 7), the prevalence ranged from 3.4% to 43.0% (pooled prevalence: 21.0%). For distress (N = 4), the prevalence ranged from 4.3% to 11.6% (pooled prevalence: 7.0%).
Prevalences of symptoms of depression, anxiety and distress among long-term survivors of cancer do not fundamentally differ from the general population. This is reassuring for primary care physicians, as they frequently act as the primary physician for long-term survivors whose follow-up schedules in the hospital have been completed.
在癌症诊断后的头几年，抑郁、焦虑和痛苦的症状很常见，但人们对这些症状的长期患病率知之甚少。本综述的目的是描述癌症长期幸存者（诊断后 5 年以上）中抑郁、焦虑和/或痛苦症状的患病率，并为初级保健提供依据。
我们在 PubMed、PsycINFO 和 CINAHL 数据库中进行了系统的文献检索。当报告关于长期癌症幸存者（诊断后≥5 年）的抑郁、焦虑和/或痛苦症状的患病率，并采用治愈性治疗时，研究才符合纳入标准。
共纳入 20 项研究。报告的抑郁症状患病率（N=18）从 5.4%到 49.0%（汇总患病率：21.0%）不等。对于焦虑（N=7），患病率从 3.4%到 43.0%（汇总患病率：21.0%）不等。对于痛苦（N=4），患病率从 4.3%到 11.6%（汇总患病率：7.0%）不等。
癌症长期幸存者的抑郁、焦虑和痛苦症状的患病率与一般人群没有根本区别。这对初级保健医生来说是令人安心的，因为他们经常作为长期幸存者的初级医生，这些长期幸存者在医院的随访计划已经完成。
