Department of Forensic Sciences, Pathological Anatomy, Gynecology and Obstetrics and Pediatrics, University of Santiago de Compostela, Santiago de Compostela, Spain.
Pediatric Metabolism and Research Unit, Department of Pediatrics, Reina Sofia University Hospital, IMIBIC, University of Cordoba, Cordoba, Spain.
Adv Nutr. 2019 May 1;10(suppl_2):S88-S96. doi: 10.1093/advances/nmy096.
There is a physiological basis for the roles of selected nutrients, especially proteins, calcium, and vitamin D, in growth and development, which are at a maximum during the pediatric period. Milk and dairy products are particularly rich in this group of nutrients. The present systematic review summarizes the available evidence relating dairy product intake with linear growth and bone mineral content in childhood and adolescence. A search was conducted in the MEDLINE (via PubMed) and SCOPUS databases following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and included intervention-controlled clinical trials with dairy products in children from 1 January, 1926 to 30 June, 2018. The risk of bias for each study was assessed using the Cochrane methodology. The number of study participants, the type of study and doses, the major outcomes, and the key results of the 13 articles included in the review are reported. The present systematic review shows that supplementing the usual diet with dairy products significantly increases bone mineral content during childhood. However, the results regarding a possible relation between dairy product consumption and linear growth are inconclusive.
有生理基础表明,某些营养素(特别是蛋白质、钙和维生素 D)在生长发育中发挥作用,而在儿童期,这些营养素的作用达到最大。牛奶和奶制品特别富含这组营养素。本系统评价总结了现有的关于乳制品摄入与儿童和青少年线性生长和骨矿物质含量的关系的证据。按照系统评价和荟萃分析的首选报告项目(PRISMA)指南,在 MEDLINE(通过 PubMed)和 SCOPUS 数据库中进行了检索,纳入了 1926 年 1 月 1 日至 2018 年 6 月 30 日期间针对儿童的乳制品干预对照临床试验。使用 Cochrane 方法评估了每项研究的偏倚风险。报告了纳入本综述的 13 篇文章的研究参与者人数、研究类型和剂量、主要结局以及关键结果。本系统评价表明,在通常饮食中补充乳制品可显著增加儿童时期的骨矿物质含量。然而,关于乳制品消费与线性生长之间可能存在关联的结果尚无定论。