Rowlands B J
Ulster Med J. 1987 Apr;56(1):13-22.
Controversy exists concerning the appropriate use of carbohydrate solutions and fat emulsions as energy sources in intravenous nutritional regimens. Current evidence suggests that glucose is the carbohydrate energy source of choice and that when infused with appropriate quantities of protein it provides cheap and effective nutritional support in the majority of patients and clinical circumstances. During glucose infusion, blood glucose and acid-base balance should be closely monitored and, when indicated, exogenous insulin should be added to the regimen to combat hyperglycaemia and improve protein anabolism. Fat emulsions, although expensive, may justifiably be used in patients with moderate or severe stress to provide up to 50% of non-protein energy, especially in circumstances where attempts to satisfy energy requirements exclusively with glucose would impose an additional metabolic stress.
在静脉营养方案中,关于碳水化合物溶液和脂肪乳剂作为能量来源的恰当使用存在争议。目前的证据表明,葡萄糖是首选的碳水化合物能量来源,并且当与适量蛋白质一起输注时,它能在大多数患者和临床情况下提供廉价且有效的营养支持。在输注葡萄糖期间,应密切监测血糖和酸碱平衡,必要时应在方案中添加外源性胰岛素以对抗高血糖并改善蛋白质合成代谢。脂肪乳剂虽然昂贵,但在中度或重度应激患者中合理使用可提供高达50%的非蛋白质能量,特别是在仅用葡萄糖来满足能量需求会带来额外代谢应激的情况下。