Kaufman D W, Palmer J R, Rosenberg L, Shapiro S
Br Med J (Clin Res Ed). 1987 May 23;294(6583):1315-6. doi: 10.1136/bmj.294.6583.1315.
The effect of cigar and pipe smoking on the risk of myocardial infarction was evaluated in an interview study of 572 men with non-fatal first myocardial infarctions and 934 hospital controls. The study was conducted in the north eastern United States from 1980 to 1983. All subjects were 40-54 years of age, and none had smoked cigarettes for at least two years. Among men who had never smoked cigarettes the relative risk of myocardial infarction for those who smoked at least five cigars a day, compared with not smoking cigars and pipes and allowing for other risk factors, was estimated to be 1.7 (95% confidence interval 0.6 to 4.8). Among ex-smokers of cigarettes the corresponding estimate for those who smoked at least five cigars a day was 4.5 (2.2 to 9.2). The estimates for men who smoked fewer cigars, or pipes, were closer to 1.0 and not significant. Men who stop smoking cigarettes and switch to at least five cigars a day apparently continue to have an increased risk of myocardial infarction, possibly because they continue to inhale the smoke.
在一项针对572名首次发生非致命性心肌梗死的男性和934名医院对照者的访谈研究中，评估了抽雪茄和烟斗对心肌梗死风险的影响。该研究于1980年至1983年在美国东北部进行。所有受试者年龄在40 - 54岁之间，且至少两年未吸烟。在从不吸烟的男性中，与不抽雪茄和烟斗并考虑其他风险因素相比，每天至少抽五支雪茄的男性发生心肌梗死的相对风险估计为1.7（95%置信区间为0.6至4.8）。在曾经吸烟的男性中，每天至少抽五支雪茄的男性相应的风险估计为4.5（2.2至9.2）。抽雪茄或烟斗较少的男性的估计值更接近1.0且无统计学意义。停止吸烟并改为每天至少抽五支雪茄的男性显然心肌梗死风险仍然增加，可能是因为他们继续吸入烟雾。
