西班牙人类临床样本中无新孢子虫 DNA。
Absence of Neospora caninum DNA in Human Clinical Samples, Spain.
出版信息
Emerg Infect Dis. 2019 Jun;25(6):1226-1227. doi: 10.3201/eid2506.181431.
Abstract
Low antibody titers to Neospora caninum have been reported in humans, but infection has not been confirmed. We used N. caninum-specific PCR to test 600 clinical samples from patients with toxoplasmosis signs but Toxoplasma gondii-negative PCR results. We did not detect N. caninum DNA, demonstrating it is an unlikely opportunistic zoonotic agent.
摘要
已有人报道人类对刚地弓形虫的抗体效价较低，但尚未确认感染。我们使用刚地弓形虫特异性 PCR 检测了 600 份来自有弓形虫病迹象但 PCR 结果为 Toxoplasma gondii 阴性的患者的临床样本。我们未检测到刚地弓形虫 DNA，表明其不太可能是机会性动物传染病原体。
相似文献
1
Absence of Neospora caninum DNA in Human Clinical Samples, Spain.西班牙人类临床样本中无新孢子虫 DNA。
Emerg Infect Dis. 2019 Jun;25(6):1226-1227. doi: 10.3201/eid2506.181431.
2
Molecular assessment of Neospora caninum and Toxoplasma gondii in hooded crows (Corvus cornix) in Tehran, Iran.伊朗德黑兰 hooded crows（冠小嘴乌鸦，学名：Corvus cornix）中新孢子虫和刚地弓形虫的分子评估
Comp Immunol Microbiol Infect Dis. 2018 Apr;57:69-73. doi: 10.1016/j.cimid.2018.06.008. Epub 2018 Jun 14.
3
Toxoplasma gondii, Neospora caninum and tick-transmitted bacterium Anaplasma phagocytophilum infections in one selected goat farm in Slovakia.斯洛伐克一个选定山羊场中的刚地弓形虫、犬新孢子虫和蜱传播细菌嗜吞噬细胞无形体感染情况。
Acta Parasitol. 2013 Dec;58(4):541-6. doi: 10.2478/s11686-013-0171-5. Epub 2013 Dec 13.
4
Presence of Toxoplasma gondii and Neospora caninum DNA in the brain of wild birds.弓形虫和新孢子虫 DNA 在野生鸟类脑部的存在。
Vet Parasitol. 2012 Feb 10;183(3-4):377-81. doi: 10.1016/j.vetpar.2011.07.024. Epub 2011 Jul 23.
5
Toxoplasma gondii and Neospora caninum in Tolai Hares (Lepus tolai) Intended for Human Consumption in China: Seroprevalence, DNA Detection, and Genotyping.中国供人类食用的托氏兔（Lepus tolai）中的刚地弓形虫和犬新孢子虫：血清阳性率、DNA检测及基因分型
Foodborne Pathog Dis. 2018 Sep;15(9):544-547. doi: 10.1089/fpd.2018.2436. Epub 2018 May 21.
6
Toxoplasma gondii and Neospora caninum in sparrows (Passer domesticus) in the Northeast of Brazil.巴西东北部麻雀（Passer domesticus）体内的刚地弓形虫和新孢子虫。
Vet Parasitol. 2010 Feb 26;168(1-2):121-4. doi: 10.1016/j.vetpar.2009.09.055. Epub 2009 Oct 9.
7
Neospora caninum: detection in wild rabbits and investigation of co-infection with Toxoplasma gondii by PCR analysis.犬新孢子虫：在野兔中的检测及通过聚合酶链反应分析调查与刚地弓形虫的共感染情况
Exp Parasitol. 2008 Nov;120(3):255-60. doi: 10.1016/j.exppara.2008.07.011. Epub 2008 Jul 30.
8
Toxoplasma gondii and Neospora caninum in wild small mammals: Seroprevalence, DNA detection and genotyping.野生小型哺乳动物中的刚地弓形虫和犬新孢子虫：血清阳性率、DNA检测及基因分型
Vet Parasitol. 2016 Jun 15;223:88-90. doi: 10.1016/j.vetpar.2016.04.018. Epub 2016 Apr 22.
9
Development of a polymerase chain reaction assay for the diagnosis of neosporosis using the Neospora caninum 14-3-3 gene.利用犬新孢子虫14-3-3基因开发用于诊断新孢子虫病的聚合酶链反应检测方法。
Mol Biochem Parasitol. 1996 Jan;75(2):169-78. doi: 10.1016/0166-6851(95)02530-8.
10
A survey of Neospora caninum and Toxoplasma gondii infection in urban rodents from Brazil.巴西城市啮齿动物中新孢子虫和刚地弓形虫感染情况的调查。
J Parasitol. 2012 Feb;98(1):128-34. doi: 10.1645/GE-2817.1. Epub 2011 Jul 26.
引用本文的文献
1
Small Biological Fighters Against Cancer: Viruses, Bacteria, Archaea, Fungi, Protozoa, and Microalgae.对抗癌症的小型生物斗士：病毒、细菌、古菌、真菌、原生动物和微藻。
Biomedicines. 2025 Mar 8;13(3):665. doi: 10.3390/biomedicines13030665.
2
and in invasive wild boars () and hunting dogs from Brazil.以及来自巴西的野猪和猎犬。 （括号内内容原文未给出完整，无法准确翻译）
Int J Parasitol Parasites Wildl. 2024 Jun 6;24:100951. doi: 10.1016/j.ijppaw.2024.100951. eCollection 2024 Aug.
3
Cytokine production by bovine adipose tissue stromal vascular fraction cells upon Neospora caninum stimulation.牛脂肪组织基质血管部分细胞在刚地弓形虫刺激下细胞因子的产生。
Sci Rep. 2024 Apr 10;14(1):8444. doi: 10.1038/s41598-024-58885-z.
4
Serological Prevalence of , , and var. in Wild Boars () Hunted in a Highly Anthropized Area in Italy.意大利一个高度城市化地区猎杀的野猪（Sus scrofa）中猪繁殖与呼吸综合征病毒（PRRSV）、猪圆环病毒2型（PCV2）和猪肺炎支原体（M. hyopneumoniae）变种的血清学流行情况
Animals (Basel). 2023 May 23;13(11):1730. doi: 10.3390/ani13111730.
5
Seroprevalence of antibodies in dogs, cows, and humans in Assiut province, Egypt: a pilot study.埃及阿斯尤特省犬、牛和人类抗体血清流行率：一项试点研究。
J Parasit Dis. 2023 Sep;47(3):677-682. doi: 10.1007/s12639-023-01612-8. Epub 2023 Jul 8.
6
Neospora caninum and Toxoplasma gondii infections in one-humped camels (Camelus dromedarius) in central desert of Iran.伊朗中部沙漠地区单峰驼（Camelus dromedarius）中刚地弓形虫和新孢子虫感染。
Parasitol Res. 2023 Mar;122(3):847-852. doi: 10.1007/s00436-023-07783-w. Epub 2023 Jan 19.
7
Molecular detection and identification of three intracellular parasites of retail mutton products in Beijing, China.中国北京零售羊肉产品中三种细胞内寄生虫的分子检测与鉴定
Front Vet Sci. 2022 Sep 30;9:1018788. doi: 10.3389/fvets.2022.1018788. eCollection 2022.
8
Molecular detection of Toxoplasma gondii and Neospora caninum in rock pigeons (Columba livia) in Punjab, Pakistan.巴基斯坦旁遮普省岩鸽（Columba livia）中弓形虫和新孢子虫的分子检测。
Parasitol Res. 2022 May;121(5):1499-1505. doi: 10.1007/s00436-022-07494-8. Epub 2022 Mar 23.
9
Indoor bacterial, fungal and viral species and functional genes in urban and rural schools in Shanxi Province, China-association with asthma, rhinitis and rhinoconjunctivitis in high school students.中国山西省城乡学校室内细菌、真菌和病毒种类及功能基因与高中生哮喘、鼻炎和鼻结膜炎的关系。
Microbiome. 2021 Jun 12;9(1):138. doi: 10.1186/s40168-021-01091-0.
10
Modeling the Ruminant Placenta-Pathogen Interactions in Apicomplexan Parasites: Current and Future Perspectives.顶复门寄生虫中反刍动物胎盘与病原体相互作用的建模：现状与未来展望
Front Vet Sci. 2021 Jan 21;7:634458. doi: 10.3389/fvets.2020.634458. eCollection 2020.
本文引用的文献
1
Serologic screening for Neospora caninum, France.法国对犬新孢子虫的血清学筛查。
Emerg Infect Dis. 2009 Jun;15(6):987-9. doi: 10.3201/eid1506.081414.
2
Detection of immunoglobulin G antibodies to Neospora caninum in humans: high seropositivity rates in patients who are infected by human immunodeficiency virus or have neurological disorders.人类中抗犬新孢子虫免疫球蛋白G抗体的检测：在感染人类免疫缺陷病毒或患有神经系统疾病的患者中血清阳性率很高。
Clin Vaccine Immunol. 2006 Jan;13(1):84-9. doi: 10.1128/CVI.13.1.84-89.2006.
3
Comparison of two DNA targets for the diagnosis of Toxoplasmosis by real-time PCR using fluorescence resonance energy transfer hybridization probes.使用荧光共振能量转移杂交探针通过实时PCR诊断弓形虫病时两种DNA靶标的比较
BMC Infect Dis. 2003 May 2;3:7. doi: 10.1186/1471-2334-3-7.
4
Single tube nested PCR for the detection of Toxoplasma gondii in fetal tissues from naturally aborted ewes.用于检测自然流产母羊胎儿组织中弓形虫的单管巢式聚合酶链反应
Vet Parasitol. 2001 Dec 3;102(1-2):17-27. doi: 10.1016/s0304-4017(01)00526-x.
5
The pathogenesis of experimental neosporosis in pregnant sheep.妊娠绵羊实验性新孢子虫病的发病机制
J Comp Pathol. 1998 May;118(4):267-79. doi: 10.1016/s0021-9975(07)80003-x.
6
Detection of Neospora from tissues of experimentally infected rhesus macaques by PCR and specific DNA probe hybridization.通过聚合酶链反应（PCR）和特异性DNA探针杂交技术从实验性感染恒河猴的组织中检测新孢子虫。
J Clin Microbiol. 1997 Jul;35(7):1740-5. doi: 10.1128/jcm.35.7.1740-1745.1997.
7
Urine sample used for congenital toxoplasmosis diagnosis by PCR.用于通过聚合酶链反应（PCR）诊断先天性弓形虫病的尿液样本。
J Clin Microbiol. 1996 Oct;34(10):2368-71. doi: 10.1128/jcm.34.10.2368-2371.1996.
8
Experimental fetal and transplacental Neospora infection in the nonhuman primate.非人灵长类动物的实验性胎儿和经胎盘新孢子虫感染
Lab Invest. 1994 Aug;71(2):236-42.
Zotero 插件