School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Small. 2019 Nov;15(48):e1901485. doi: 10.1002/smll.201901485. Epub 2019 May 21.
Single-atom catalysts are becoming a hot research topic owing to their unique characteristics of maximum specific activity and atomic utilization. Herein, a new single-atom nanozyme (SAN) based on single Fe atoms anchored on N-doped carbons supported on carbon nanotube (CNT/FeNC) is proposed. The CNT/FeNC with robust atomic Fe-N moieties is synthesised, showing superior peroxidase-like activity. Furthermore, the CNT/FeNC is used as the signal element in a series of paper-based bioassays for ultrasensitive detection of H O , glucose, and ascorbic acid. The SAN provides a new type of signal element for developing various biosensing techniques.
单原子催化剂因其具有最大比活性和原子利用率等独特特性，正在成为一个热门的研究课题。在此，提出了一种基于负载在碳纳米管上的氮掺杂碳载体上锚定的单个铁原子的新型单原子纳米酶（SAN）。合成了具有强原子 Fe-N 部分的 CNT/FeNC，表现出优异的过氧化物酶样活性。此外，将 CNT/FeNC 用作一系列基于纸张的生物测定中的信号元件，用于超灵敏检测 H2O2、葡萄糖和抗坏血酸。该单原子纳米酶为开发各种生物传感技术提供了一种新型信号元件。
