Miyake K, Sugiyama S, Norimatsu I, Ozawa T
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Dec 15;209(2):83-8. doi: 10.1007/BF00407841.
The amounts of Prostaglandin (PG) E and F2alpha in the aqueous humor were measured by radioimmunoassay techniques before and immediately after intracapsular and extracapsular cataract extractions. We found that: 1. The levels of PG E and PG F2alpha are elevated by cataract extraction. 2. The elevated levels of PGs can all be prevented by preoperative applications of topical indomethacin. 3. No differences in the amounts of PGs biosynthesized during intracapsular and extracapsular lens extraction were found. 4. In some cases, the levels of PG E were still elevated one week after surgery. These findings were used as the basis for our attempts to define the causes of cystoid macular edema (CME) following lens extractions.
采用放射免疫测定技术，在囊内和囊外白内障摘除术前及术后即刻测量房水中前列腺素（PG）E和F2α的含量。我们发现：1. 白内障摘除可使PG E和PG F2α水平升高。2. 术前局部应用吲哚美辛可预防PG水平升高。3. 囊内和囊外晶状体摘除过程中生物合成的PG量未发现差异。4. 在某些病例中，术后一周PG E水平仍升高。这些发现作为我们试图确定晶状体摘除术后黄斑囊样水肿（CME）病因的依据。
