Namiki M, Nakamura M, Okuyama A, Itatani H, Sonoda T, Matsumoto K
Clin Endocrinol (Oxf). 1986 Nov;25(5):495-500. doi: 10.1111/j.1365-2265.1986.tb03601.x.
In order to investigate the relationship between testicular FSH receptors and the effectiveness of hMG-hCG treatment in idiopathic male infertility, 36 infertile men were examined. None of the 13 patients without detectable testicular high affinity FSH receptors showed any increase in motile sperm count after the hMG-hCG treatment, whereas 11 of the 23 patients with FSH receptors responded to the treatment. In patients with FSH receptors, patients with a middle or high Johnsen's score count responded more than those with a low score count did. From the above results, it seems that both the presence or absence of testicular FSH receptors and the histological appearance of spermatogenesis predict responsiveness to hMG-hCG treatment in infertile men.
为了研究睾丸促卵泡激素（FSH）受体与hMG-hCG治疗特发性男性不育症疗效之间的关系，对36名不育男性进行了检查。13例未检测到睾丸高亲和力FSH受体的患者在hMG-hCG治疗后，活动精子计数均未增加，而23例有FSH受体的患者中有11例对治疗有反应。在有FSH受体的患者中，约翰森评分中等或高的患者比评分低的患者反应更明显。根据上述结果，似乎睾丸FSH受体的有无以及精子发生的组织学表现都可以预测不育男性对hMG-hCG治疗的反应。
