Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga, 520-2192, Japan.
Department of Hygiene, Wakayama Medical University, Wakayama, Japan.
Environ Health Prev Med. 2019 May 28;24(1):37. doi: 10.1186/s12199-019-0788-6.
The gender-specific characteristics of individuals at an increased risk of developing depression currently remain unclear despite a higher prevalence of depression in women than in men. This study clarified socioeconomic and lifestyle factors associated with an increased risk of subclinical depression in general Japanese men and women.
Study participants were residents not receiving psychiatric treatments in 300 sites throughout Japan in 2010 (1152 men, 1529 women). Multivariable-adjusted odds ratios (OR) and 95% confidence intervals (95%CIs) for socioeconomic factors and lifestyle factors were calculated using a logistic regression analysis.
Risk of depressive tendencies was significantly higher in men who were single and living alone (OR, 3.27; 95% CI, 1.56-6.88) than those married. The risk was significantly lower in women who were not working and aged ≥ 60 years (OR, 0.39; 95% CI, 0.22-0.68) and higher in men who were not working and aged < 60 years (OR, 3.57; 95%CI, 1.31-9.72) compared with those who were working. Current smoking was also associated with a significantly increased risk of depressive tendencies in women (OR, 2.96; 95% CI, 1.68-5.22) but not in men.
Socioeconomic and lifestyle factors were associated with an increased risk of depressive tendencies in general Japanese. Related factors were different by sex.
尽管女性抑郁症的患病率高于男性,但目前仍不清楚处于抑郁症高发风险的个体的性别特异性特征。本研究旨在明确与一般日本男性和女性亚临床抑郁症风险增加相关的社会经济和生活方式因素。
2010 年,在日本 300 个地点的未接受精神治疗的居民中(男性 1152 人,女性 1529 人)进行了这项研究。使用逻辑回归分析计算了社会经济因素和生活方式因素与亚临床抑郁症风险增加相关的多变量调整比值比(OR)和 95%置信区间(95%CI)。
与已婚男性相比,单身且独居的男性发生抑郁倾向的风险显著更高(OR,3.27;95%CI,1.56-6.88)。与在职女性相比,未工作且年龄≥60 岁的女性(OR,0.39;95%CI,0.22-0.68)和未工作且年龄<60 岁的男性(OR,3.57;95%CI,1.31-9.72)发生抑郁倾向的风险显著更低。与在职女性相比,不吸烟的女性(OR,2.96;95%CI,1.68-5.22)和不吸烟的男性(OR,1.47;95%CI,0.84-2.58)发生抑郁倾向的风险显著更高。
社会经济和生活方式因素与一般日本人群的抑郁倾向风险增加相关。相关因素因性别而异。