Akpinar Melis, Ocal Meric, Irdem Ahmet
Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey.
Department of Pediatrics, Okmeydani Training and Research Hospital, Istanbul, Turkey.
J Electrocardiol. 2019 Jul-Aug;55:116-119. doi: 10.1016/j.jelectrocard.2019.05.013. Epub 2019 May 21.
Breath holding spells is a non-epileptic paroxysmal disease which is frequently seen in childhood. In this study, we aimed to investigate electrocardiographic atrial conduction and ventricular repolarization changes in children with breath holding spells.
We reviewed the electrocardiograms of 58 patients with breath holding spells who admitted to SBU Okmeydanı SUAM Pediatric Cardiology Clinic between November 2018 and February 2019. QT, QTc (calculated with Bazett formula), T peak-end (Tp-e), QT dispersion (QTd), QTc dispersion (QTcd), Tp-e/QT ratio, Tp-e/QTc ratio, JT interval, JTc (calculated with Bazett formula), Tp-e/JT ratio, Tp-e/JTc ratio and P dispersion (Pd) were measured and compared with the control group of 44 healthy children.
In the control and the case groups, mean QTd was 19.86 ms and 38.57 ms, QTcd was 28.34 ms and 58.03 ms, Tp-e/QT ratio was 0.16 and 0.26, Tp-e/QTc ratio was 0.11 and 0.17, JT interval was 204.09 ms and 224.52 ms, JTc value was 290.00 ms and 333.72 ms, Tp-e/JT ratio was 0.23 and 0.35, Tp-e/JTc ratio was 0.16 and 0.24, Pd was 29.32 ms and 40.53 ms respectively. Differences between two groups were statistically significant (p < 0,001).
QTd, QTcd, Tp-e, Tp-e/QT ratio, Tp-e/QTc ratio, JT, JTc, Tp-e/JT, Tp-e/JTc ratio and Pd were increased significantly compared to healthy children. Based on the results, ventricular repolarization and atrial conduction were affected in patients with breath holding spells. These patients may be under the risk of developing rhythm disorders.
屏气发作是一种常见于儿童期的非癫痫性发作性疾病。在本研究中，我们旨在调查屏气发作患儿的心电图心房传导和心室复极变化。
我们回顾了2018年11月至2019年2月期间入住SBU奥克梅伊达尼SUAM儿科心脏病诊所的58例屏气发作患者的心电图。测量了QT、QTc（用Bazett公式计算）、T峰-末间期（Tp-e）、QT离散度（QTd）、QTc离散度（QTcd）、Tp-e/QT比值、Tp-e/QTc比值、JT间期、JTc（用Bazett公式计算）、Tp-e/JT比值、Tp-e/JTc比值和P波离散度（Pd），并与44名健康儿童的对照组进行比较。
在对照组和病例组中，平均QTd分别为19.86毫秒和38.57毫秒，QTcd分别为28.34毫秒和58.03毫秒，Tp-e/QT比值分别为0.16和0.26，Tp-e/QTc比值分别为0.11和0.17，JT间期分别为204.09毫秒和224.52毫秒，JTc值分别为290.00毫秒和333.72毫秒，Tp-e/JT比值分别为0.23和0.35，Tp-e/JTc比值分别为0.16和0.24，Pd分别为29.32毫秒和40.53毫秒。两组间差异有统计学意义（p<0.001）。
与健康儿童相比，屏气发作患者的QTd、QTcd、Tp-e、Tp-e/QT比值、Tp-e/QTc比值、JT、JTc、Tp-e/JT、Tp-e/JTc比值和Pd显著增加。基于这些结果，屏气发作患者的心室复极和心房传导受到影响。这些患者可能有发生心律失常的风险。
