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Four new caffeoylgluconic acid positional isomers from the fruits of .

作者信息

Wang Liang, Wang Dai-Jie, Guo Wei, Sun Kai-Bin, Huang Na-Na, Sun Rong

机构信息

School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine , Jinan 250355 , China.

Shandong Academy of Chinese Medicine , Jinan 250014 , China.

出版信息

J Asian Nat Prod Res. 2019 Nov;21(11):1104-1111. doi: 10.1080/10286020.2019.1621854. Epub 2019 Jun 1.

DOI:10.1080/10286020.2019.1621854
PMID:31154872
Abstract

Four new compounds, 4---caffeoylgluconic acid (), 2---caffeoylgluconic acid (), 3---caffeoylgluconic acid (), 5---caffeoylgluconic acid (), together with three known ones including 6---caffeoylgluconic acid (), neochlorogenic acid (), chlorogenic acid () were obtained from the fruits of . Their structure elucidation was achieved by the methods of spectroscopic analyses, including HR-ESI-MS, NMR, and by comparison with literatures. The hepatotoxicity of compounds was evaluated by CCK-8 method. [Formula: see text].

摘要

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