Melton L J, O'Fallon W M, Riggs B L
Department of Medical Statistics and Epidemiology, Mayo Clinic, Rochester, Minnesota 55905.
Calcif Tissue Int. 1987 Aug;41(2):57-64. doi: 10.1007/BF02555245.
To explore possible changes in proximal femur (hip) fracture incidence over time, an earlier study among Rochester, Minnesota residents for 1928-1977 was updated through 1982. Reanalysis of data demonstrated rising age-adjusted rates for men over this time. Crude rates rose for women as well, but age adjusted rates leveled off in the mid-1950s, as did overall rates, since the majority of hip fractures were in women. Secular trends were primarily due to changes in the incidence of initial hip fractures associated with moderate trauma, the sort usually attributed to osteoporosis. No differences were noted in trends for cervical vs. intertrochanteric femur fractures; and, excluding the low values for 1928-1942, no significant trends were noted for women within various age groups. Our results for women conflict with estimates from a number of other studies, but these differences may provide a basis for hypothesis development.
为探究股骨近端（髋部）骨折发病率随时间的可能变化，一项针对明尼苏达州罗切斯特市居民1928 - 1977年情况的早期研究更新至1982年。对数据的重新分析表明，在此期间男性年龄调整发病率呈上升趋势。女性的粗发病率也有所上升，但年龄调整发病率在20世纪50年代中期趋于平稳，总体发病率也是如此，因为大多数髋部骨折发生在女性身上。长期趋势主要归因于与中度创伤相关的初始髋部骨折发病率的变化，这种创伤通常归因于骨质疏松症。在颈椎与转子间股骨骨折的趋势方面未发现差异；并且，排除1928 - 1942年的低值，各年龄组女性未发现显著趋势。我们关于女性的研究结果与其他一些研究的估计结果相冲突，但这些差异可能为假设的提出提供依据。
