Nazir Shabnam, Azim Marium
Kohat University of Science and Technology, Kohat, KPK, Pakistan.
Department of Pharmaceutical Sciences, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa (KPK), Pakistan.
Eur J Hosp Pharm. 2017 Jul;24(4):200-203. doi: 10.1136/ejhpharm-2015-000733. Epub 2016 May 24.
Self-medication with antibiotics is a common practice, which may lead to the development of antimicrobial resistance (AMR)-a major health concern worldwide. The most common reason for the development of AMR is a lack of education and regulatory policies and the lack of community pharmacists.
To assess various factors that lead to self-medication with antibiotics, which might cause AMR and hinder effective healthcare.
A cross-sectional study was carried out using a predesigned questionnaire to collect data from 800 respondents. The respondents were selected by simple random sampling during November 2014 to January 2015 from different regions of Khyber Pakhtunkhwa (KPK), Pakistan. Only properly completed questionnaires were assessed for different variables. The collected data were analysed using SPSS V.16.
527 people completed and returned the questionnaire-a response rate of 66%. Self-medication with antibiotics was reported by 135 participants (26%), with a higher prevalence of men than women (48% vs 38%, respectively). The main reason for self-medication was previous experience with the same antibiotic (68%). The most commonly used antibiotics were amoxicillin-clavulanate (40%) and major indications for self-medication were sore throat (29%) and flu (24%). Of the 527 respondents, only 104 (20%) were aware of AMR.
This study is the first to evaluate self-medication with antibiotics in KPK, Pakistan. In view of the high prevalence of self-medication, introduction of a public health policy through drug regulatory authorities, public awareness programmes/campaigns, patient education about AMR and appropriate use of antibiotics are critically required. The role of community pharmacists needs to be strengthened.
自行使用抗生素是一种常见现象,这可能会导致抗菌药物耐药性(AMR)的产生——这是全球主要的健康问题。AMR产生的最常见原因是缺乏教育和监管政策以及社区药剂师的短缺。
评估导致自行使用抗生素的各种因素,这些因素可能会导致AMR并阻碍有效的医疗保健。
采用预先设计的问卷进行横断面研究,以收集800名受访者的数据。2014年11月至2015年1月期间,通过简单随机抽样从巴基斯坦开伯尔-普赫图赫瓦省(KPK)的不同地区选取受访者。仅对填写完整的问卷进行不同变量的评估。使用SPSS V.16对收集到的数据进行分析。
527人完成并返回了问卷,回复率为66%。135名参与者(26%)报告有自行使用抗生素的情况,男性的患病率高于女性(分别为48%和38%)。自行用药的主要原因是以前使用过相同的抗生素(68%)。最常用的抗生素是阿莫西林-克拉维酸(40%),自行用药的主要适应症是喉咙痛(29%)和流感(24%)。在527名受访者中,只有104人(20%)了解AMR。
本研究是首次在巴基斯坦开伯尔-普赫图赫瓦省评估自行使用抗生素的情况。鉴于自行用药的高患病率,迫切需要通过药品监管机构出台公共卫生政策、开展公众意识项目/活动、对患者进行关于AMR和抗生素合理使用的教育。社区药剂师的作用需要得到加强。