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小肠胃肠道出血的诊断与管理——一篇叙述性综述

Small Bowel Gastrointestinal Bleeding Diagnosis and Management-A Narrative Review.

作者信息

Murphy B, Winter D C, Kavanagh D O

机构信息

Department of Colorectal Surgery, University Hospital Tallaght, Dublin, Ireland.

Department of Colorectal Surgery, St. Vincent's University Hospital, Dublin, Ireland.

出版信息

Front Surg. 2019 May 16;6:25. doi: 10.3389/fsurg.2019.00025. eCollection 2019.

Abstract

Small bowel bleeding accounts for 5-10% of all gastrointestinal bleeding. Despite advances in imaging, endoscopy and minimally invasive therapeutic techniques, its diagnosis and treatment remains a challenge and a standardized algorithm for approaching suspected small bowel bleeding remains elusive. Furthermore, the choice of investigation is subject to timing of presentation and accessibility to investigations. The aim of this study was to construct a narrative review of recent literature surrounding the diagnosis and management of small bowel bleeding. A literature review was conducted examining the database pubmed with the following key words and Boolean operators: occult GI bleed OR mesenteric bleed OR gastrointestinal hemorrhage OR GI hemorrhage AND management. Articles were selected and reviewed based on relevance to the research topic. Where necessary, the full text was sought to further assess relevance. In overt GI bleeding, CT angiography and red cell scintigraphy are both feasible and reliable diagnostic imaging modalities if standard endoscopy is negative. Red cell scintigraphy may be advantageous through detection of lower bleeding rates but it is subject to availability. Overt bleeding and a positive CT angiogram or red cell scan improves the diagnostic yield of formal angiography ± embolization. Video capsule endoscopy or double balloon endoscopy can be considered in occult GI bleeding following normal upper and lower endoscopy. Small bowel bleeding remains a rare but significant diagnostic and therapeutic challenge. Technological advances in diagnostics have aided evaluation but have not broadened the range of therapeutic interventions.

摘要

小肠出血占所有胃肠道出血的5%-10%。尽管在影像学、内镜检查和微创治疗技术方面取得了进展,但其诊断和治疗仍然是一项挑战,且尚未形成用于处理疑似小肠出血的标准化算法。此外,检查方法的选择取决于就诊时间和检查的可及性。本研究的目的是对近期有关小肠出血诊断和管理的文献进行叙述性综述。通过使用以下关键词和布尔运算符在PubMed数据库中进行文献检索:隐匿性胃肠道出血或肠系膜出血或胃肠道出血或胃肠道大出血以及管理。根据与研究主题的相关性选择并审阅文章。必要时,查找全文以进一步评估相关性。在显性胃肠道出血中,如果标准内镜检查结果为阴性,CT血管造影和红细胞闪烁扫描都是可行且可靠的诊断成像方式。红细胞闪烁扫描通过检测较低的出血率可能具有优势,但受可用性限制。显性出血以及CT血管造影或红细胞扫描结果为阳性可提高正式血管造影±栓塞的诊断率。在上下消化道内镜检查正常后的隐匿性胃肠道出血中,可考虑使用视频胶囊内镜或双气囊内镜。小肠出血仍然是一个罕见但重要的诊断和治疗挑战。诊断技术的进步有助于评估,但尚未拓宽治疗干预的范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6532547/e8fcb9716e74/fsurg-06-00025-g0001.jpg

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