使用针对铜绿假单胞菌蛋白F的单克隆抗体作为调理素，促进巨噬细胞的吞噬作用。
Use of monoclonal antibodies to protein F of Pseudomonas aeruginosa as opsonins for phagocytosis by macrophages.
作者信息
Battershill J L, Speert D P, Hancock R E
机构信息
Department of Microbiology, University of British Columbia, Vancouver, Canada.
出版信息
Infect Immun. 1987 Oct;55(10):2531-3. doi: 10.1128/iai.55.10.2531-2533.1987.
Abstract
Five protein F-specific monoclonal antibodies were found to opsonize Pseudomonas aeruginosa for complement-independent phagocytosis by unelicited mouse peritoneal macrophages, mouse macrophage cell line P388D1, and human monocyte-derived macrophages. Immunoglobulin G1 antibodies seemed to be a preferred isotype.
摘要
发现五种蛋白质F特异性单克隆抗体可调理铜绿假单胞菌，使其被未致敏的小鼠腹腔巨噬细胞、小鼠巨噬细胞系P388D1和人单核细胞衍生的巨噬细胞进行非补体依赖性吞噬作用。免疫球蛋白G1抗体似乎是一种优选的同种型。
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