影响常见细菌分离株耐药性的流行病学因素。
Epidemiologic factors affecting antimicrobial resistance of common bacterial isolates.
作者信息
Ellner P D, Fink D J, Neu H C, Parry M F
机构信息
Clinical Microbiology and Laboratory Information Services, The Presbyterian Hospital, New York, New York.
出版信息
J Clin Microbiol. 1987 Sep;25(9):1668-74. doi: 10.1128/jcm.25.9.1668-1674.1987.
The pattern of antimicrobial resistance of common bacterial isolates obtained from various groups of patients at a large tertiary-care center was compared with the pattern of resistance seen at a primary-care community hospital. At the tertiary-care center, significant differences in susceptibility were seen between pediatric and adult groups. In the tertiary-care center, the inpatients were more likely than the outpatients to have resistant staphylococcal and enterobacterial strains. Comparison of the overall resistance at the tertiary-care center and the primary-care hospital showed that resistance to cephalosporins, piperacillin, and aminoglycosides was significantly higher at the tertiary-care hospital than at the community hospital. Striking differences were noted in the resistance of nosocomial Enterobacter and Citrobacter isolates. Hospitals should be cautious in extrapolating nationwide data to their particular institutions.
在一家大型三级医疗中心，对从不同患者群体中分离出的常见细菌菌株的抗菌耐药模式，与一家初级保健社区医院的耐药模式进行了比较。在三级医疗中心，儿科和成人组之间的药敏性存在显著差异。在三级医疗中心，住院患者比门诊患者更有可能携带耐药葡萄球菌和肠杆菌菌株。对三级医疗中心和初级保健医院的总体耐药性进行比较后发现，三级医疗医院对头孢菌素、哌拉西林和氨基糖苷类药物的耐药性显著高于社区医院。在医院获得性肠杆菌和柠檬酸杆菌分离株的耐药性方面发现了显著差异。医院在将全国性数据外推至其特定机构时应谨慎行事。
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