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澳大利亚白种人样本中免疫球蛋白单倍型Gm1,17;23;21和Gm1,2,17;23;21的出现情况。

Occurrence of the immunoglobulin haplotypes Gm1,17;23;21 and Gm1,2,17;23;21 in a sample of Australian Caucasians.

作者信息

Propert D N, Janardhana V

机构信息

Department of Applied Biology, Royal Melbourne Institute of Technology, Victoria, Australia.

出版信息

J Immunogenet. 1987 Feb;14(1):73-8. doi: 10.1111/j.1744-313x.1987.tb00364.x.

Abstract

Phenotypes positive for G2m(23) but negative for G1m(3) and G3m(5,10,11,13,14) are generally very infrequent in Caucasian populations. We recently Gm typed 372 Australian blood donors, predominantly of European descent, and found two Gm(1;23) and five Gm(1,2;23) individuals among them. This finding suggests that the haplotypes Gm1,17;23;21 and Gm1,2,17;23;21 may occur, in some European populations, with a frequency considerably higher than has been generally assumed.

摘要

在高加索人群中,G2m(23)呈阳性但G1m(3)和G3m(5,10,11,13,14)呈阴性的表型通常非常罕见。我们最近对372名澳大利亚献血者进行了Gm分型,这些献血者主要为欧洲血统,结果在他们当中发现了两名Gm(1;23)个体和五名Gm(1,2;23)个体。这一发现表明,单倍型Gm1,17;23;21和Gm1,2,17;23;21在某些欧洲人群中的出现频率可能比普遍认为的要高得多。

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