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Replication-Coupled DNA Repair.
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Impediments to replication fork movement: stabilisation, reactivation and genome instability.
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3
Repair and tolerance of DNA damage at the replication fork: A structural perspective.
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Removal of RTF2 from Stalled Replisomes Promotes Maintenance of Genome Integrity.
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Preventing replication fork collapse to maintain genome integrity.
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PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.
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Replication fork instability and the consequences of fork collisions from rereplication.
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Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
Nat Genet. 2017 Apr;49(4):537-549. doi: 10.1038/ng.3790. Epub 2017 Feb 13.
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Maintaining genome stability at the replication fork.
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Working on Genomic Stability: From the S-Phase to Mitosis.
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Mechanisms and genomic implications of break-induced replication.
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Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation.
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Comprehensive interrogation of synthetic lethality in the DNA damage response.
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SUMOylation promotes protective responses to DNA-protein crosslinks.
EMBO J. 2019 Apr 15;38(8). doi: 10.15252/embj.2019101496. Epub 2019 Mar 26.
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TRAIP is a master regulator of DNA interstrand crosslink repair.
Nature. 2019 Mar;567(7747):267-272. doi: 10.1038/s41586-019-1002-0. Epub 2019 Mar 6.
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Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1.
J Cell Biol. 2019 Apr 1;218(4):1235-1249. doi: 10.1083/jcb.201810058. Epub 2019 Feb 12.
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The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.
Cell. 2019 Jan 10;176(1-2):167-181.e21. doi: 10.1016/j.cell.2018.10.053. Epub 2018 Dec 27.
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Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts.
Mol Cell. 2019 Feb 7;73(3):574-588.e7. doi: 10.1016/j.molcel.2018.11.024. Epub 2018 Dec 27.
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Replisome Dynamics and Their Functional Relevance upon DNA Damage through the PCNA Interactome.
Cell Rep. 2018 Dec 26;25(13):3869-3883.e4. doi: 10.1016/j.celrep.2018.11.099.
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HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA.
Cell. 2019 Jan 10;176(1-2):144-153.e13. doi: 10.1016/j.cell.2018.10.055. Epub 2018 Dec 13.
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Imaging cellular responses to antigen tagged DNA damage.
DNA Repair (Amst). 2018 Nov;71:183-189. doi: 10.1016/j.dnarep.2018.08.023. Epub 2018 Aug 23.
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An intrinsic S/G checkpoint enforced by ATR.
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