Alluvala Shobha A, Aziz Nuzhat, Tumkur Ashwin, Boorugu Hari K
1Department of Obstetrics, Fernandez Hospital, 4-1-1230, Bogulkunta, Abids, Hyderabad, 500001 India.
2Consultant Interventional Cardiologist, Fernandez Hospital, 4-1-1230, Bogulkunta, Abids, Hyderabad, 500001 India.
J Obstet Gynaecol India. 2019 Jun;69(3):211-217. doi: 10.1007/s13224-018-1157-x. Epub 2018 Jul 23.
Some women experience unforeseen complications during pregnancy and childbirth, which may be life threatening; their survival depends on intensive support and timely interventions. The aim of this study was to assess the long-term prevalence of adverse health conditions and their impact on quality of life in women who had severe acute maternal morbidity (SAMM).
This is a prospective cohort study comprising 43 women with SAMM during 2015 (exposure group) and 43 women who had an uneventful pregnancy and delivery (non-exposure group) during the same study period. Those who consented were given an additional follow-up date for free medical health check at 1 year.
The incidence of SAMM during study period was 8.6/1000 births. There were five deaths in the exposure group. Adverse health events were seen in 30 (78.94%) out of 38 survivors. Abnormal lipid profile, thrombocytopenia, cardiac diastolic dysfunction, amenorrhoea, Sheehan and Asherman syndrome were major findings in the exposed group. Four (10.52%) women required re-admission, and eight (20.05%) required additional procedures to confirm screening abnormalities. The exposure group had higher mean scores on the EPDS scale, incidence of suicidal thoughts and poorer performance in the WHOQOL BREF psychological domain.
Health programmes need to focus on maternal health, provide medical treatment and psychological support for a longer duration than the traditional 6 weeks postpartum in women who experience SAMM.
一些女性在怀孕和分娩期间会出现意外并发症,这可能危及生命;她们的生存依赖于强化支持和及时干预。本研究的目的是评估严重急性孕产妇发病(SAMM)女性不良健康状况的长期患病率及其对生活质量的影响。
这是一项前瞻性队列研究,包括2015年期间患有SAMM的43名女性(暴露组)和在同一研究期间怀孕和分娩顺利的43名女性(非暴露组)。同意参与的人会获得在1年后进行免费医疗健康检查的额外随访日期。
研究期间SAMM的发病率为8.6/1000例分娩。暴露组有5例死亡。38名幸存者中有30例(78.94%)出现不良健康事件。血脂异常、血小板减少、心脏舒张功能障碍、闭经、希恩综合征和阿谢曼综合征是暴露组的主要发现。4名(10.52%)女性需要再次入院,8名(20.05%)女性需要额外的检查来确诊筛查异常。暴露组在爱丁堡产后抑郁量表(EPDS)上的平均得分更高,有自杀念头的发生率更高,并且在世界卫生组织生存质量简表(WHOQOL BREF)心理领域的表现更差。
健康项目需要关注孕产妇健康,为经历SAMM的女性提供比传统产后6周更长时间的医疗治疗和心理支持。