Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Pharmacogenomics. 2019 Jun;20(8):581-587. doi: 10.2217/pgs-2019-0006.
Patients' use of and experience with pharmacogenetic (PGx) testing may be impacted by several factors including patient and provider knowledge, health status, and perceived understanding of results. We conducted an online survey of individuals who had subscribed to a newsletter service offered by a US commercial PGx testing company, Genelex. We find that about half of respondents that had PGx testing reviewed one or more of the lab's web-pages, 43% believed they understood the test results very well, but 40% did not know or could not recall whether their provider had changed their prescription based on the test result. There was limited use of the laboratory's online resources by respondents undergoing PGx testing. Increased awareness of the website may improve understanding of test results and facilitate discussions with providers about medication changes.
患者对药物遗传学(PGx)检测的使用和体验可能受到多种因素的影响,包括患者和提供者的知识、健康状况以及对结果的理解程度。我们对订阅了美国商业 PGx 检测公司 Genelex 提供的新闻通讯服务的个人进行了在线调查。我们发现,大约一半接受过 PGx 检测的受访者查看了实验室的一个或多个网页,43%的人表示他们非常了解检测结果,但 40%的人不知道或无法回忆起他们的医生是否根据检测结果改变了他们的处方。接受 PGx 检测的受访者对实验室的在线资源的使用有限。提高对网站的认识可能有助于提高对检测结果的理解,并促进与提供者就药物治疗变化进行讨论。