患者在基层医疗环境中进行药物遗传学检测的经历。
Patient experiences with pharmacogenetic testing in a primary care setting.
作者信息
Haga Susanne B, Mills Rachel, Moaddeb Jivan, Allen Lapointe Nancy, Cho Alex, Ginsburg Geoffrey S
机构信息
Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Durham, NC 27708, USA.
Duke Clinical Research Institute, Duke University, Durham, NC 22708, USA.
出版信息
Pharmacogenomics. 2016 Oct;17(15):1629-1636. doi: 10.2217/pgs-2016-0077. Epub 2016 Sep 20.
AIM
To investigate patient experiences with pharmacogenetic (PGx) testing.
METHODS
Patients were offered PGx testing through a study on pharmacist-assisted delivery of PGx testing and invited to complete pre- and post-testing surveys about their experience.
RESULTS
Of 63 patients tested, 17 completed the baseline survey (27%). Interest in testing was mostly impacted by desire to inform selection of best treatment (n = 13). Seven of 12 patients that completed the follow-up survey indicated that their provider discussed the test result with them. Five patients understood their test result very or somewhat well. All would be likely to have PGx testing again.
CONCLUSION
Patients perceived PGx testing to be useful, though more effort may be needed to improve patient-provider communication of test results.
目的
调查患者进行药物遗传学（PGx）检测的体验。
方法
通过一项关于药剂师辅助进行PGx检测的研究，为患者提供PGx检测，并邀请他们完成检测前和检测后的体验调查。
结果
在接受检测的63名患者中，17名完成了基线调查（27%）。对检测的兴趣主要受到希望为选择最佳治疗提供依据的影响（n = 13）。在完成随访调查的12名患者中，7名表示其医疗服务提供者与他们讨论了检测结果。5名患者对其检测结果理解得非常好或较好。所有人都可能会再次进行PGx检测。
结论
患者认为PGx检测有用，不过可能需要付出更多努力来改善医疗服务提供者与患者之间关于检测结果的沟通。
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