血清心脏标志物与业余运动员在耐力训练适应性反应中的最大摄氧量呈负相关。
Serum cardiac markers are inversely associated with VOmax of amateur athletes in response to endurance training adaptations.
作者信息
Tesema Gashaw, George Mala, Mondal Soumitra, Mathivana D
机构信息
Department of Sport Science, College of Natural and Computational Science, Mizan-Tepi University, Mizan, Ethiopia.
Department of Sport Science, College of Natural and Computetional Science, Mekelle University, Mekelle, Ethiopia.
出版信息
BMJ Open Sport Exerc Med. 2019 Apr 9;5(1):e000537. doi: 10.1136/bmjsem-2019-000537. eCollection 2019.
BACKGROUND
The influence of endurance training intensity and adaptation on serum cardiac markers is poorly understood and controversial; however, no enough data observed the association of serum cardiac markers with VOmax. Therefore, we aimed to investigate whether serum cardiac markers are associated with maximum oxygen consumption (VOmax) in response to 12-week endurance training on amateur athletes.
METHODS
15 apparently healthy male amateur athletes with 19.47 ± 1.30 years of age were recruited and participated in endurance training with 70%-80% maximal heart rate intensity for 35 min per session for the first week and 2 min increments each week from the second to the last week for a period of 12 weeks. VOmax and serum cardiac markers (lactate dehydrogenase [LDH], creatine kinase myocardial band (CK-MB) and cardiac troponin I [CTnI]) were assessed at the beginning of the training and after 12-week endurance training.
RESULTS
The result of CTnI indicated significantly (p < 0.01) and inversely (r = - 0.466) correlated with VOmax and CK-MB indicated significantly (p < 0.01) and inversely associated with VOmax (r = - 0.536) with moderate relationship. However, we did not find a significant association on LDH (p > 0.05) with VOmax in response to endurance training adaptation.
CONCLUSION
Our finding confirms our hypothesis that serum cardiac markers are inversely associated with estimated VOmax in response to endurance training adaptation.
背景
耐力训练强度和适应性对血清心脏标志物的影响尚不清楚且存在争议；然而，尚无足够数据观察血清心脏标志物与最大摄氧量（VO₂max）之间的关联。因此，我们旨在研究在业余运动员进行12周耐力训练后，血清心脏标志物是否与最大摄氧量（VO₂max）相关。
方法
招募15名年龄为19.47±1.30岁的明显健康男性业余运动员，第一周参加以最大心率强度的70%-80%进行的耐力训练，每次训练35分钟，从第二周到最后一周每周增加2分钟，为期12周。在训练开始时和12周耐力训练后评估VO₂max和血清心脏标志物（乳酸脱氢酶[LDH]、肌酸激酶同工酶（CK-MB）和心肌肌钙蛋白I[CTnI]）。
结果
CTnI结果显示与VO₂max显著负相关（p<0.01，r=-0.466），CK-MB与VO₂max显著负相关（p<0.01，r=-0.536），呈中度相关。然而，在耐力训练适应性方面，我们未发现LDH与VO₂max有显著关联（p>0.05）。
结论
我们的研究结果证实了我们的假设，即在耐力训练适应性方面，血清心脏标志物与估计的VO₂max呈负相关。
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