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细胞因子作为评估训练和非训练个体身体活动的生物标志物:一个叙事性综述。

Cytokines as Biomarkers for Evaluating Physical Exercise in Trained and Non-Trained Individuals: A Narrative Review.

机构信息

Institute of Physical Culture Sciences, University of Szczecin, 71-065 Szczecin, Poland.

Doctoral School, University of Szczecin, 70-384 Szczecin, Poland.

出版信息

Int J Mol Sci. 2023 Jul 6;24(13):11156. doi: 10.3390/ijms241311156.

Abstract

Physical activity and exercise training have numerous health benefits, including the prevention and management of chronic diseases, improvement of cardiovascular health, and enhancement of mental well-being. However, the effectiveness of training programs can vary widely among individuals due to various factors, such as genetics, lifestyle, and environment. Thus, identifying reliable biomarkers to evaluate physical training effectiveness and personalize training programs is crucial. Cytokines are signaling molecules produced by immune cells that play a vital role in inflammation and tissue repair. In recent years, there has been increasing interest in the potential use of cytokines as biomarkers for evaluating training effectiveness. This review article aims to provide an overview of cytokines, their potential as biomarkers, methods for measuring cytokine levels, and factors that can affect cytokine levels. The article also discusses the potential benefits of using cytokines as biomarkers, such as monitoring muscle damage and inflammation, and the potential for personalized training programs based on cytokine responses. We believe that the use of cytokines as biomarkers holds great promise for optimizing training programs and improving overall health outcomes.

摘要

身体活动和运动训练有许多健康益处,包括预防和管理慢性疾病、改善心血管健康和增强心理健康。然而,由于遗传、生活方式和环境等各种因素,训练计划的效果在个体之间差异很大。因此,确定可靠的生物标志物来评估身体训练的效果并使训练计划个性化至关重要。细胞因子是免疫细胞产生的信号分子,在炎症和组织修复中起着至关重要的作用。近年来,人们对细胞因子作为评估训练效果的生物标志物的潜在用途越来越感兴趣。本文旨在提供细胞因子的概述,它们作为生物标志物的潜力、测量细胞因子水平的方法以及影响细胞因子水平的因素。本文还讨论了将细胞因子作为生物标志物的潜在益处,例如监测肌肉损伤和炎症,以及根据细胞因子反应制定个性化训练计划的潜力。我们相信,将细胞因子作为生物标志物用于优化训练计划和改善整体健康结果具有巨大的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b82/10342447/b428b25f0359/ijms-24-11156-g001.jpg

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