Tesema Gashaw, George Mala
Sport Science, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
Biochemistry, Arba Minch University, Arba Minch, Southern Nations, Ethiopia.
BMJ Open Sport Exerc Med. 2021 Mar 18;7(1):e001065. doi: 10.1136/bmjsem-2021-001065. eCollection 2021.
Previous studies were conducted only on elite athletes, and they investigate acute training responses of cardiac troponin I (CTnI). However, cardiac troponin was found to be elevated in young and inexperienced athletes than adults, and immature myocardium is more susceptible to injury, which needs further consideration.
Therefore, we aimed to observe the association between CTnI and cardiovascular parameters in response to chronic endurance training adaptation in young athletes.
Fifteen participants aged (19.5±1.3) years were selected and placed in endurance running at 70%-80% HRmax intensity for 35 min per training for the first week and additional 2 min each week from the second to the last week for 12 weeks. Serum cardiac troponin and cardiovascular parameters were assessed at pre-training and after 12 weeks of training.
We find a significant CTnI level (p<0.05) and it is positively correlated with systolic blood pressure (BP) (r=0.425). Moreover, CTnI was statistically significant (p<0.01) and positively associated with mean arterial pressure (r=0.516) with a moderate correlation. Besides, CTnI showed a significant (p<0.001) and positive relationship with resting heart rate (r=0.605) and a moderate correlation. We did not find a significant relationship between CTnI and diastolic BP in response to endurance training adaptation.
In conclusion, serum CTnI was significantly and positively associated with cardiovascular parameters in young amateur athletes in response to 12-week endurance training adaptation.
以往研究仅针对精英运动员，且研究了心肌肌钙蛋白I（CTnI）的急性训练反应。然而，发现年轻且缺乏经验的运动员的心肌肌钙蛋白水平高于成年人，并且未成熟的心肌更容易受到损伤，这需要进一步考虑。
因此，我们旨在观察年轻运动员在慢性耐力训练适应过程中CTnI与心血管参数之间的关联。
选取15名年龄为（19.5±1.3）岁的参与者，第一周以70%-80%最大心率（HRmax）强度进行35分钟的耐力跑训练，从第二周到最后一周每周增加2分钟，共训练12周。在训练前和训练12周后评估血清心肌肌钙蛋白和心血管参数。
我们发现CTnI水平有显著变化（p<0.05），且与收缩压（BP）呈正相关（r=0.425）。此外，CTnI具有统计学意义（p<0.01），与平均动脉压呈正相关（r=0.516），相关性中等。此外，CTnI与静息心率呈显著正相关（p<0.001，r=0.605），相关性中等。在耐力训练适应过程中，我们未发现CTnI与舒张压之间存在显著关系。
总之，在年轻业余运动员中，经过12周耐力训练适应后，血清CTnI与心血管参数显著正相关。
