阿尔及利亚布利达大学医院儿科收治的儿童急性下呼吸道感染的病毒学研究。

Virologic study of acute lower respiratory tract infections in children admitted to the paediatric department of Blida University Hospital, Algeria.

作者信息

Derrar F, Izri K, Kaddache C, Boukari R, Hannoun D

机构信息

Viral Respiratory Unit, Virology Department, Institut Pasteur of Algeria, Algiers, Algeria.

Paediatric Department, University Hospital of Blida, Blida, Algeria.

出版信息

New Microbes New Infect. 2019 Mar 27;30:100536. doi: 10.1016/j.nmni.2019.100536. eCollection 2019 Jul.

DOI:10.1016/j.nmni.2019.100536

PMID:31193119

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6517316/

Abstract

Acute lower respiratory tract infections (ALRTI) such as pneumonia and bronchiolitis are major causes of mortality and morbidity in children under 5 years of age. The main microbial agents responsible for ALRTI are either bacterial agents ( type b, ) or viruses (respiratory syncytial virus (RSV, also known as human orthopneumovirus), adenovirus) [1]. More recently, other viruses (rhinovirus, metapneumovirus, coronavirus, bocavirus) have been implicated in ALRTI; their identification has been facilitated by new molecular biology techniques such as real-time PCR. To our knowledge, these emerging viruses have never been the subject of epidemiologic studies in our country.

摘要

急性下呼吸道感染（ALRTI），如肺炎和支气管炎，是5岁以下儿童死亡和发病的主要原因。导致ALRTI的主要微生物病原体要么是细菌病原体（b型），要么是病毒（呼吸道合胞病毒（RSV，也称为人正肺病毒）、腺病毒）[1]。最近，其他病毒（鼻病毒、偏肺病毒、冠状病毒、博卡病毒）也被认为与ALRTI有关；新型分子生物学技术如实时PCR有助于对它们的识别。据我们所知，这些新出现的病毒在我国从未成为流行病学研究的对象。