在尼日利亚儿童急性呼吸道疾病中检测到的特定病毒。
Specific viruses detected in nigerian children in association with acute respiratory disease.
机构信息
Viral Infections Unit, Department of Vaccination and Immune Protection, National Institute for Health and Welfare (THL), Helsinki, Finland.
出版信息
J Trop Med. 2011;2011:690286. doi: 10.1155/2011/690286. Epub 2011 Oct 11.
Abstract
Occurrence of different viruses in acute respiratory tract infections of Nigerian children was examined. Respiratory swabs were collected from 246 children referred to hospital clinics because of acute respiratory symptoms from February through May 2009. Validated real-time RT-PCR techniques revealed nucleic acids of at least one virus group in 189 specimens (77%). Human rhinoviruses and parainfluenza viruses were present each in one third of the children. Adenoviruses, enteroviruses, human metapneumovirus, human bocavirus, and influenza C virus were also relatively common. Possibly due to their seasonal occurrence, influenza A and B virus, and respiratory syncytial virus were detected rarely. We conclude that all major groups of respiratory tract viruses are causing illness in Nigerian children.
摘要
本研究旨在调查尼日利亚儿童急性呼吸道感染中不同病毒的发生情况。2009 年 2 月至 5 月，我们采集了 246 例因急性呼吸道症状而到医院就诊的儿童的呼吸道拭子。经过验证的实时 RT-PCR 技术显示，189 份标本（77%）中至少存在一种病毒群的核酸。人类鼻病毒和副流感病毒在三分之一的儿童中均存在。腺病毒、肠道病毒、人偏肺病毒、人博卡病毒和丙型流感病毒也较为常见。可能由于其季节性发病，甲型和乙型流感病毒以及呼吸道合胞病毒的检出率较低。本研究得出结论，所有主要的呼吸道病毒群均会导致尼日利亚儿童发病。
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