Br Med J (Clin Res Ed). 1987 Oct 24;295(6605):1044-7. doi: 10.1136/bmj.295.6605.1044.
In a case-control study 27 index children from ordinary schools who had had convulsions or apnoea as a complication of whooping cough about eight years previously were compared with 27 children who had never had whooping cough and 15 who had had whooping cough without complications. Other factors likely to cause intellectual impairment after conception were considered. The index group had a significantly lower median intelligence quotient and poorer school attainment than either of the control groups. The results support the hypothesis that convulsions or apnoea as a complication of whooping cough may be associated with subsequent intellectual impairment.
在一项病例对照研究中,将27名约8年前患百日咳并伴有惊厥或呼吸暂停并发症的普通学校受试儿童,与27名从未患过百日咳的儿童以及15名患过百日咳但无并发症的儿童进行了比较。研究考虑了其他可能导致受孕后智力障碍的因素。受试组的智商中位数显著低于两个对照组,学业成绩也比对照组差。这些结果支持了以下假设:百日咳并发症引起的惊厥或呼吸暂停可能与随后的智力障碍有关。