Br Med J (Clin Res Ed). 1985 Jun 29;290(6486):1937-40. doi: 10.1136/bmj.290.6486.1937.
Eight hundred and thirteen children who had had whooping cough when under 5 years of age in the 1977-9 epidemic were compared with a control group roughly four and a half years later, each child being matched by age and sex and from the same class in school. The index group showed long term respiratory sequelae of whooping cough--namely, deterioration in lung function, increase in respiratory symptoms, and increased admission to hospital for both upper and lower respiratory conditions. Asthma was significantly more common in the index group, suggesting that asthma was being regarded as a contraindication to pertussis vaccination. Only 3.5% of the asthmatic children in the index group had been vaccinated as against 29.1% of the controls.
对1977 - 199年疫情期间5岁以下患百日咳的813名儿童，约四年半后与一个对照组进行比较，每个儿童按年龄、性别匹配且来自同一班级。指标组显示出百日咳的长期呼吸道后遗症，即肺功能恶化、呼吸道症状增加以及因上、下呼吸道疾病住院次数增加。哮喘在指标组中明显更为常见，这表明哮喘被视为百日咳疫苗接种的禁忌证。指标组中只有3.5%的哮喘儿童接种过疫苗，而对照组为29.1%。
