Hadi Muhammad Abdul, McHugh Gretl A, Closs S José
Leicester School of Pharmacy, De Montfort University, Leicester, United Kingdom.
School of Healthcare, University of Leeds, Leeds, United Kingdom.
J Patient Exp. 2019 Jun;6(2):133-141. doi: 10.1177/2374373518786013. Epub 2018 Jul 5.
Chronic pain has become a common problem within primary care and can negatively impact patients' lives.
To assess and explore the impact of chronic pain on patients' quality of life (QoL) using quantitative and qualitative data, respectively.
A convergent parallel mixed-methods design was used. Chronic pain patients were recruited from a community-based pain clinic located in the North of England. Quality of life was assessed using Short-Form 36 version 2. Quality of life data were also extracted from the Third Oxford and Lifestyles Survey and Welsh Health Survey to allow comparison of QoL of chronic pain patients with that of the general population and patients with long-term conditions. Qualitative interviews were conducted face-to-face using a semistructured topic guide. Quantitative data were analyzed using SPSS version 24 and qualitative data were analyzed thematically.
Seventy-nine patients participated in the quantitative phase. The mean (standard deviation) age was 46.5 (14.5). Lower back (54; 68.3%) followed by lower limb were the most common pain sites. Compared with the general population and patients with long-term conditions, chronic pain patients had significantly lower mean QoL scores across all domains of SF-36 (All < .05). Six themes emerged from qualitative data: interference with physical functioning, interference with professional life, interference with relationships and family life, interference with social life, interference with sleep, and interference with mood.
The multidimensional negative impact of chronic pain leads to poorer QoL among patients with chronic pain compared to the general population and patients with other long-term conditions.
慢性疼痛已成为初级保健中的常见问题，会对患者生活产生负面影响。
分别使用定量和定性数据评估并探讨慢性疼痛对患者生活质量（QoL）的影响。
采用了一种收敛性平行混合方法设计。从位于英格兰北部的一家社区疼痛诊所招募慢性疼痛患者。使用简明健康调查问卷第2版评估生活质量。还从第三次牛津生活方式调查和威尔士健康调查中提取生活质量数据，以便将慢性疼痛患者的生活质量与普通人群和患有长期疾病的患者进行比较。使用半结构化主题指南进行面对面的定性访谈。使用SPSS 24版分析定量数据，对定性数据进行主题分析。
79名患者参与了定量阶段。平均（标准差）年龄为46.5（14.5）岁。下背部（54例；68.3%）其次是下肢是最常见的疼痛部位。与普通人群和患有长期疾病的患者相比，慢性疼痛患者在SF-36所有领域的平均生活质量得分均显著较低（均P<0.05）。定性数据中出现了六个主题：对身体功能的干扰、对职业生活的干扰、对人际关系和家庭生活的干扰、对社交生活的干扰、对睡眠的干扰以及对情绪的干扰。
与普通人群和患有其他长期疾病的患者相比，慢性疼痛的多维度负面影响导致慢性疼痛患者的生活质量较差。
