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一名溃疡性结肠炎患者因硫胺素缺乏导致的视神经病变。

Optic neuropathy from thiamine deficiency in a patient with ulcerative colitis.

作者信息

van Noort B A, Bos P J, Klopping C, Wilmink J M

机构信息

Department of Ophthalmology, University of Amsterdam, The Netherlands.

出版信息

Doc Ophthalmol. 1987 Sep-Oct;67(1-2):45-51. doi: 10.1007/BF00142696.

DOI:10.1007/BF00142696
PMID:3123189
Abstract

A 35-year-old man with ulcerative colitis who was receiving parenteral feeding with large amounts of glucose, suddenly developed severe optic neuropathy and oculomotor palsy. The visual acuity fell bilaterally to 0. Although it was stated that thiamine has been regularly supplemented in the preceding period, high doses of vitamin B1 were given. Visual acuity promptly returned to 1.0 but large visual field defects persisted. Later on it appeared that erroneously no vitamin B1 has been given before.

摘要

一名35岁患有溃疡性结肠炎的男子,正在接受大量葡萄糖的肠外营养支持,突然出现严重的视神经病变和动眼神经麻痹。双眼视力降至零。尽管据称在此之前已定期补充硫胺素,但仍给予了高剂量的维生素B1。视力迅速恢复到1.0,但大的视野缺损仍然存在。后来发现之前错误地未给予维生素B1。

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Optic neuropathy in Wernicke encephalopathy: More than meets the eye?韦尼克脑病中的视神经病变:表象之下另有隐情?

本文引用的文献

1
Current concepts. Wernicke's encephalopathy.当前概念。韦尼克脑病。
N Engl J Med. 1985 Apr 18;312(16):1035-9. doi: 10.1056/NEJM198504183121606.
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Wernicke encephalopathy following prolonged intravenous therapy.
JAMA. 1976 May 31;235(22):2403-5.
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Vitamin metabolism and therapy in ophthalmology.眼科中的维生素代谢与治疗
Surv Ophthalmol. 1979 Nov-Dec;24(3):177-90. doi: 10.1016/0039-6257(79)90021-3.
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14th EUNOS Congress: PORTO, PORTUGAL, 16-19 JUNE 2019.第14届欧洲神经肿瘤学会大会:葡萄牙波尔图,2019年6月16日至19日。
Neuroophthalmology. 2019 Jun 7;43(Suppl 1):1-221. doi: 10.1080/01658107.2019.1608780. eCollection 2019 Jun.
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Treatment and Outcomes in Nutritional Optic Neuropathy.营养性视神经病变的治疗与转归
Curr Treat Options Neurol. 2019 Feb 7;21(1):5. doi: 10.1007/s11940-019-0542-9.
6
Vitamins and Minerals in Inflammatory Bowel Disease.炎症性肠病中的维生素和矿物质。
Gastroenterol Clin North Am. 2017 Dec;46(4):797-808. doi: 10.1016/j.gtc.2017.08.011. Epub 2017 Oct 3.
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Visual loss and optic nerve head swelling in thiamine deficiency without prolonged dietary deficiency.无长期饮食缺乏情况下硫胺素缺乏所致的视力丧失和视神经乳头肿胀
Clin Ophthalmol. 2014 May 22;8:1021-4. doi: 10.2147/OPTH.S64228. eCollection 2014.