Section of Gastrointestinal Surgical Oncology, Peritoneal Surface Malignancy Program, Division of Surgical Oncology, Johns Hopkins University, 600 N. Wolfe Street/Blalock 606, Baltimore, MD, 21287, USA.
Department of Surgery, Johns Hopkins Hospital, 600 N. Wolfe Street/Blalock 665, Baltimore, MD, 21287, USA.
Curr Oncol Rep. 2019 Jun 24;21(8):67. doi: 10.1007/s11912-019-0820-4.
Gastric adenocarcinoma is the fifth most common and the third most lethal cancer worldwide. Surgery is the only chance of cure, but recurrence is common, even with complete resection.
Advances in diagnosis and staging, genomic classification, surgical resection and treatment of peritoneal disease, systemic chemotherapy and chemoradiation, and targeted and immune therapies have led to the current multidisciplinary approach to gastric adenocarcinoma. Treatment of gastric cancer is rapidly evolving in an effort to combat this challenging disease.
胃腺癌是全球第五大常见癌症,也是第三大最致命癌症。手术是唯一的治愈机会,但即使完全切除,仍常复发。
在诊断和分期、基因组分类、手术切除和治疗腹膜疾病、全身化疗和放化疗、靶向和免疫治疗方面的进展,使得当前对胃腺癌采用了多学科方法。为了攻克这一具有挑战性的疾病,胃癌的治疗正在迅速发展。