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酷似转移性肝肿瘤的肝异尖线虫病

Hepatic anisakiasis mimicking metastatic liver tumour.

作者信息

Kita Ryosuke, Hashida Hiroki, Uryuhara Kenji, Kaihara Satoshi

机构信息

Department of Surgery, Kobe City Medical Center General Hospital, Japan.

出版信息

Int J Surg Case Rep. 2019;60:209-212. doi: 10.1016/j.ijscr.2019.06.010. Epub 2019 Jun 12.

DOI:10.1016/j.ijscr.2019.06.010
PMID:31238201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6598741/
Abstract

INTRODUCTION

Anisakiasis is a parasitic disease caused by anisakid nematode larvae, which are found in raw or undercooked fish. It occurs more frequently in the digestive tract, but has also been reported outside the gastrointestinal tract. This report details a case of rare hepatic anisakiasis that was initially diagnosed as metastatic rectal cancer.

PRESENTATION OF CASE

A 60-year-old male underwent radical resection for stage III rectal cancer followed by adjuvant chemotherapy for six months. Seven months after surgery, a new, 10 mm diameter area of low density was seen in segment 4/8 margin of the liver on enhanced computed tomography (CT) scan. Metastatic liver tumour from rectal cancer was suspected. Laparoscopic partial hepatectomy was performed. The diagnosis was revised to hepatic anisakiasis when pathological examination revealed anisakis simplex larvae in the necrotic tissue.

DISCUSSION

Anisakiasis outside of the gastrointestinal tract is a rare finding, but may be seen more frequently with the recent increase in the consumption of raw fish around the world. Hepatic anisakiasis may mimic tumours in the liver. Clinicians should consider dietary inquiry and further evaluation in patients with liver margin tumours less than 20 mm in size that are not positively malignant, as hepatic anisakiasis may be a possible diagnosis.

CONCLUSION

We report a rare case of hepatic anisakiasis which initially presented as suspected metastatic cancer. Hepatic anisakiasis should be considered in the differential diagnosis of low density liver tumours less than 20 mm, where the patient's diet includes raw fish.

摘要

引言

异尖线虫病是一种由异尖线虫幼虫引起的寄生虫病,这些幼虫存在于生的或未煮熟的鱼类中。它在消化道中更为常见,但也有在胃肠道外被报道的情况。本报告详细介绍了一例罕见的肝脏异尖线虫病病例,该病例最初被诊断为转移性直肠癌。

病例介绍

一名60岁男性接受了III期直肠癌根治性切除术,随后进行了六个月的辅助化疗。术后七个月,增强计算机断层扫描(CT)显示肝脏第4/8段边缘有一个新的直径10毫米的低密度区域。怀疑是直肠癌肝转移瘤。进行了腹腔镜部分肝切除术。病理检查在坏死组织中发现简单异尖线虫幼虫后,诊断改为肝脏异尖线虫病。

讨论

胃肠道外的异尖线虫病是一种罕见的发现,但随着近年来全球生鱼消费量的增加,可能会更频繁地出现。肝脏异尖线虫病可能会模仿肝脏肿瘤。对于肝边缘肿瘤大小小于20毫米且未确诊为恶性的患者,临床医生应考虑询问饮食情况并进行进一步评估,因为肝脏异尖线虫病可能是一种可能的诊断。

结论

我们报告了一例罕见的肝脏异尖线虫病病例,最初表现为疑似转移性癌症。对于饮食中包括生鱼的小于20毫米的低密度肝脏肿瘤的鉴别诊断,应考虑肝脏异尖线虫病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/a7d9384e0ae0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/c0dcfc92889f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/1631e189baae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/a7d9384e0ae0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/c0dcfc92889f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/1631e189baae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae9f/6598741/a7d9384e0ae0/gr3.jpg

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