Department of Periodontology, Faculty of Dentistry, Bingöl University, Bingöl, Turkey.
Department of Periodontology, Faculty of Dentistry, Harran University, Şanlıurfa, Turkey.
Med Sci Monit. 2019 Jun 26;25:4744-4750. doi: 10.12659/MSM.915142.
BACKGROUND This study investigated the potential effects of Injectable Platelet-Rich Fibrin (I-PRF) on root coverage of free gingival graft surgery. MATERIAL AND METHODS A total of 40 patients with Miller class I or II gingival recession were included. The patients who participated in this study were randomly divided into 2 groups, including the control and experiment groups. The patients in the control group were treated only with free gingival graft (FGG). The patients in the experiment group were treated with free gingival graft and injected with I-PRF as a root surface biomodification agent (FGG+I-PRF). The patients were called back after 3 months, and the amount of exposed root surface was determined and compared to the preoperative findings. RESULTS The mean initial exposed root surface was 4.7±1.49 mm for the FGG+I-PRF group, 4.1±1.07 mm for the FGG group, and 4.4±1.31 mm for all subjects. Three months after the operation, the mean root surface coverage values of the 2 groups were 3.5±1.05 and 3.9±0.78 mm in the control and experiment groups, respectively. CONCLUSIONS The findings showed that the injection of Injectable Platelet-Rich Fibrin (I-PRF) had a positive effect on root coverage in free gingival graft surgery.
本研究旨在探讨注射用富血小板纤维蛋白（I-PRF）对游离龈瓣移植术根面覆盖的潜在影响。
共纳入 40 例 Miller 分类 I 或 II 型牙龈退缩患者。将参与本研究的患者随机分为两组，即对照组和实验组。对照组患者仅接受游离龈瓣移植术（FGG）治疗。实验组患者接受游离龈瓣移植术联合注射 I-PRF 作为根面生物改性剂（FGG+I-PRF）治疗。术后 3 个月对患者进行回访，测量并比较暴露根面的量。
FGG+I-PRF 组初始暴露根面的平均长度为 4.7±1.49mm，FGG 组为 4.1±1.07mm，所有患者的平均长度为 4.4±1.31mm。术后 3 个月，两组的根面覆盖平均长度分别为 3.5±1.05mm 和 3.9±0.78mm。
研究结果表明，注射用富血小板纤维蛋白（I-PRF）对游离龈瓣移植术的根面覆盖具有积极影响。
