Leijonmarck C E, Bergstrand L O, Carlstedt-Duke B, Gustafsson A, Midtvedt A C, Norin K E, Saxerholt H, Midtvedt T
Dept. of Surgery, St Görans Hospital, Stockholm, Sweden.
Scand J Gastroenterol. 1988 Jan;23(1):59-64. doi: 10.3109/00365528809093848.
The effect of total parenteral nutrition (TPN) on the following six intestinal microflora-associated characteristics (MACs) was studied in patients with Crohn's disease: faecal tryptic activity (FTA), formation of coprostanol, urobilinogen, and deoxycholic acid, and degradation of mucin and beta-aspartylglycine. The FTA showed high levels before TPN, in accordance with previous findings, and decreased during TPN. Formation of coprostanol, urobilinogen, and deoxycholic acid was reduced in some patients, whereas no changes were found in the mucin and beta-aspartylglycine degradation.
在克罗恩病患者中研究了全胃肠外营养（TPN）对以下六种肠道微生物群相关特征（MACs）的影响：粪便胰蛋白酶活性（FTA）、粪甾烷醇、尿胆原和脱氧胆酸的形成，以及粘蛋白和β-天冬氨酰甘氨酸的降解。与之前的研究结果一致，FTA在TPN前水平较高，在TPN期间降低。一些患者的粪甾烷醇、尿胆原和脱氧胆酸的形成减少，而粘蛋白和β-天冬氨酰甘氨酸的降解未发现变化。
