Paz Tal, Rappoport Daniel, Hilely Assaf, Leiba Hana
Ophthalmology Department, Kaplan Medical Center, Rehovot, Israel.
The Hebrew University Hadassah Medical School, Jerusalem, Israel.
Clin Med Insights Case Rep. 2019 Jun 18;12:1179547619855388. doi: 10.1177/1179547619855388. eCollection 2019.
Several case reports of transient drug-induced myopia have been reported, mainly due to sulfa drugs. We present a case of a sudden and significant increase in myopia associated with initiation of Sulfasalazine for long-standing ulcerative colitis in an adult Caucasian female.
Our patient presented to the emergency room with acute bilateral visual loss. Ocular examination was normal, except for myopia of -4 Diopters (D) in both eyes (BE). The patient was advised to stop the medication, and her vision improved within 4 days to best corrected visual acuity (BCVA) of 6/7.5 with a refractive correction of -0.75 D in her right eye (RE) and BCVA of 6/6 with a refractive correction of -0.50 D in her left eye (LE).
To the best of our knowledge, this is the second reported case of transient Sulfasalazine-induced myopia.
已有数例药物性短暂性近视的病例报告，主要由磺胺类药物引起。我们报告一例成年白人女性因长期溃疡性结肠炎开始服用柳氮磺胺吡啶后出现近视突然且显著加重的病例。
我们的患者因急性双眼视力丧失就诊于急诊室。眼部检查正常，仅双眼近视4屈光度（D）。建议患者停药，4天内其视力改善，右眼（RE）最佳矫正视力（BCVA）为6/7.5，屈光度矫正为-0.75 D，左眼（LE）BCVA为6/6，屈光度矫正为-0.50 D。
据我们所知，这是第二例柳氮磺胺吡啶引起的短暂性近视报告病例。
