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通过电刺激耳蜗对人类耳鸣进行暂时性抑制。

Temporary tinnitus suppression in man through electrical stimulation of the cochlea.

作者信息

Portmann M, Cazals Y, Negrevergne M, Aran J M

出版信息

Acta Otolaryngol. 1979 Mar-Apr;87(3-4):294-9. doi: 10.3109/00016487909126423.

DOI:10.3109/00016487909126423
PMID:312586
Abstract

While investigating the possibilities of electrically induced hearing in cases of profound deafness, we observed that very often an appropriate stimulation of the cochlea could result in tinnitus cancellation. We present here a progress report on that phenomenon, including 15 subjects. Such a cancellation was restricted to tinnitus subjectively localized in the ear under test, we observed no effect on noises localized in the other ear, or centrally. This suppression occurred so long as the cochlea was stimulated and stopped when the stimulation ceased. This phenomenon was very reproducible and did not seem to affect simultaneous normal acoustic hearing. It is hypothesized that this phenomenon acts through an inhibition of abnormal activity of sensorineural elements of the electrically stimulated cochlea.

摘要

在研究深度耳聋病例中电诱发听力的可能性时,我们观察到,对耳蜗进行适当刺激常常会使耳鸣消失。在此,我们给出关于该现象的进展报告,涉及15名受试者。这种耳鸣消失仅限于主观定位在受试耳内的耳鸣,我们观察到对定位在另一只耳朵或中枢的噪声没有影响。只要刺激耳蜗,这种抑制就会发生,刺激停止时抑制也随之停止。这种现象具有很高的可重复性,而且似乎不影响同时存在的正常听觉。据推测,该现象是通过抑制电刺激耳蜗的感觉神经元件的异常活动而起作用的。

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Systematic Review on Intra- and Extracochlear Electrical Stimulation for Tinnitus.关于耳蜗内和耳蜗外电刺激治疗耳鸣的系统评价
Brain Sci. 2021 Oct 24;11(11):1394. doi: 10.3390/brainsci11111394.
3
Prognostic Value of Trial Round Window Stimulation for Selection of Candidates for Cochlear Implantation as Treatment for Tinnitus.
试验性圆窗刺激对选择人工耳蜗植入治疗耳鸣患者的预后价值
J Clin Med. 2021 Aug 25;10(17):3793. doi: 10.3390/jcm10173793.
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Changes in Tinnitus by Cochlear Implantation: A Parametric Study of the Effect of Single-Electrode Stimulation.耳蜗植入后耳鸣的变化:单电极刺激效果的参数研究。
Audiol Neurootol. 2021;26(3):140-148. doi: 10.1159/000509202. Epub 2020 Sep 7.
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Excitation of the Auditory System as a Result of Non-invasive Extra-Cochlear Stimulation in Normal Subjects and Tinnitus Patients.正常受试者和耳鸣患者非侵入性耳蜗外刺激对听觉系统的激发作用
Front Neurosci. 2018 Mar 23;12:146. doi: 10.3389/fnins.2018.00146. eCollection 2018.
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An Increase in Alpha Band Frequency in Resting State EEG after Electrical Stimulation of the Ear in Tinnitus Patients-A Pilot Study.耳鸣患者耳部电刺激后静息态脑电图中α波频段频率增加——一项初步研究
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Sensorineural Tinnitus: Its Pathology and Probable Therapies.感音神经性耳鸣:其病理学及可能的治疗方法
Int J Otolaryngol. 2016;2016:2830157. doi: 10.1155/2016/2830157. Epub 2016 Feb 8.
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