Dowsett A B, Roff M A, Greenaway P J, Elphick E R, Farrar G H
Experimental Pathology Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, Wiltshire, UK.
AIDS. 1987 Sep;1(3):147-50.
An HIV-1 isolate (designated GB8) was isolated from an asymptomatic AIDS patient and subsequently grown in the T-lymphocyte cell line JM. Electron microscopy showed that it is vesicles within the syncytia present in cultures of JM cells chronically infected with GB8, rather than the surface membranes of unfused cells, which are the major sites for the assembly, production and release of HIV.
一株HIV-1分离株（命名为GB8）从一名无症状艾滋病患者体内分离出来，随后在T淋巴细胞系JM中培养。电子显微镜显示，在长期感染GB8的JM细胞培养物中，HIV组装、产生和释放的主要部位是合胞体内的囊泡，而非未融合细胞的表面膜。
