Vasconcelos Joana, Torres João, Granado Joana, Baptista Teresa, Mansinho Kamal
Department of Infectious Diseases, Hospital Egas Moniz, Lisbon, Portugal.
IDCases. 2019 Jun 11;17:e00570. doi: 10.1016/j.idcr.2019.e00570. eCollection 2019.
Cutaneous leishmaniasis (CL) is the most common leishmaniasis syndrome, yet a neglected disease in industrialized non-endemic countries, where it has become an emergent problem. The lack of clinical experience, evidence-based literature and availability of some treatments complicates its management. We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate complex (subgenus ). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research.
皮肤利什曼病（CL）是最常见的利什曼病综合征，但在工业化非流行国家却是一种被忽视的疾病，在这些国家它已成为一个新出现的问题。临床经验的缺乏、循证文献以及某些治疗方法的可及性使得其管理变得复杂。我们报告了一例30岁男性从巴西回国后出现皮肤溃疡性病变的CL病例，在该病例中成功分离出了复合体（亚属）。最初尝试使用米替福新进行一个疗程的治疗，但考虑到无反应，改用脂质体两性霉素B，效果非常好。我们的报告强调了非流行国家在诊断和治疗新大陆CL时面临的障碍以及对更多资金和研究的需求。
