Lee C T, Tham S N, Tan T
Middle Road Hospital, Singapore.
Ann Acad Med Singap. 1987 Oct;16(4):713-5.
CO2 laser was first used in the treatment of melanomas in animals. Since then, it has been successfully used in treating many dermatological conditions. A total of 47 patients were treated once as outpatients in Middle Road Hospital by using Model 720 Sharplan CO2 Laser System and Yoshida Opelaser-01 CO2 Laser System to determine the usefulness of CO2 laser in the treatment of various dermatological conditions. The laser was used mainly in the defocused mode at 10 watts. Local anaesthetic with 1% lignocaine HCL was employed in all cases. 3 patients defaulted follow-up. Of the 30 patients with warts, most of which were recalcitrant, 14 were cured and the remaining 16 showed marked improvement. 4 of the 5 patients with lichen simplex chronicus were cured. 1 patient each of the following conditions were also treated; prurigo nodularis, psoriasis, solar keratosis, ingrowing toe nail, Bowen's disease, infected callosity and lichen amyloidosis; cure was achieved in the former 4 conditions. The laser failed to cure 2 patients with pyogenic granuloma. Side effects included hypopigmentation (62%), mild post-operative pain (11%), scarring (11%), excess granulation tissue (11%), and infection (2%). CO2 laser is a potentially useful, effective and safe treatment modality for many dermatological conditions.
二氧化碳激光最初用于动物黑色素瘤的治疗。从那时起，它已成功用于治疗多种皮肤病。中路医院共对47例门诊患者使用Sharplan 720型二氧化碳激光系统和吉田Opelaser - 01型二氧化碳激光系统进行单次治疗，以确定二氧化碳激光在治疗各种皮肤病方面的有效性。激光主要以10瓦的散焦模式使用。所有病例均采用1%盐酸利多卡因局部麻醉。3例患者未进行随访。在30例疣患者中，大多数为顽固性疣，14例治愈，其余16例有明显改善。5例慢性单纯性苔藓患者中有4例治愈。对以下每种疾病各1例患者进行了治疗：结节性痒疹、银屑病、日光性角化病、嵌甲、鲍温病、感染性胼胝和苔藓样淀粉样变；前4种疾病均治愈。激光未能治愈2例化脓性肉芽肿患者。副作用包括色素减退（62%）、轻度术后疼痛（11%）、瘢痕形成（11%）、过度肉芽组织增生（11%）和感染（2%）。二氧化碳激光对于多种皮肤病来说是一种潜在有用、有效且安全的治疗方式。
