Roberts Aled D, Finnigan William, Wolde-Michael Emmanuel, Kelly Paul, Blaker Jonny J, Hay Sam, Breitling Rainer, Takano Eriko, Scrutton Nigel S
Manchester Institute of Biotechnology, Manchester Synthetic Biology Research Centre SYBIOCHEM, School of Chemistry, The University of Manchester, Manchester, UK, M1 7DN.
Bio-Active Materials Group, School of Materials, The University of Manchester, Manchester, UK, M13 9PL.
MRS Commun. 2019 May 15;9(2):486-504. doi: 10.1557/mrc.2019.35. Epub 2019 Apr 24.
Synthetic biology has huge potential to produce the next generation of advanced materials by accessing previously unreachable (bio)chemical space. In this prospective review, we take a snapshot of current activity in this rapidly developing area, focussing on prominent examples for high-performance applications such as those required for protective materials and the aerospace sector. The continued growth of this emerging field will be facilitated by the convergence of expertise from a range of diverse disciplines, including molecular biology, polymer chemistry, materials science and process engineering. This review highlights the most significant recent advances and address the cross-disciplinary challenges currently being faced.
合成生物学通过开拓此前难以触及的(生物)化学空间,在生产下一代先进材料方面具有巨大潜力。在这篇前瞻性综述中,我们简要介绍了这个快速发展领域的当前研究活动,重点关注高性能应用的突出实例,如防护材料和航空航天领域所需的应用。包括分子生物学、高分子化学、材料科学和过程工程在内的一系列不同学科的专业知识融合,将推动这个新兴领域的持续发展。本综述突出了近期最重要的进展,并探讨了当前面临的跨学科挑战。