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上干阻滞:一种膈神经保留的肌间沟阻滞替代方法:一项随机对照试验。

Superior Trunk Block: A Phrenic-sparing Alternative to the Interscalene Block: A Randomized Controlled Trial.

机构信息

From the Departments of Anesthesiology (D.H.K., Y.L., J.C.B., J.L., J.A.O., S.C.H., M.C.H., D.S.W., L.W., C.G., S.G.M.) Orthopedic Surgery (A.A.A.), Hospital for Special Surgery, New York, New York.

出版信息

Anesthesiology. 2019 Sep;131(3):521-533. doi: 10.1097/ALN.0000000000002841.

Abstract

BACKGROUND

Interscalene nerve blockade remains one of the most commonly used anesthetic and analgesic approaches for shoulder surgery. The high incidence of hemidiaphragmatic paralysis associated with the block, however, precludes its use among patients with compromised pulmonary function. To address this issue, recent studies have investigated phrenic-sparing alternatives that provide analgesia. None, however, have been able to reliably demonstrate surgical anesthesia without significant risk for hemidiaphragmatic paralysis. The utility of the superior trunk block has yet to be studied. The hypothesis was that compared with the interscalene block, the superior trunk block will provide noninferior surgical anesthesia and analgesia while sparing the phrenic nerve.

METHODS

This randomized controlled trial included 126 patients undergoing arthroscopic ambulatory shoulder surgery. Patients either received a superior trunk block (n = 63) or an interscalene block (n = 63). The primary outcomes were the incidence of hemidiaphragmatic paralysis and worst pain score in the recovery room. Ultrasound was used to assess for hemidiaphragmatic paralysis. Secondary outcomes included noninvasively measured parameters of respiratory function, opioid consumption, handgrip strength, adverse effects, and patient satisfaction.

RESULTS

The superior trunk group had a significantly lower incidence of hemidiaphragmatic paralysis compared with the interscalene group (3 of 62 [4.8%] vs. 45 of 63 [71.4%]; P < 0.001, adjusted odds ratio 0.02 [95% CI, 0.01, 0.07]), whereas the worst pain scores in the recovery room were noninferior (0 [0, 2] vs. 0 [0, 3]; P = 0.951). The superior trunk group were more satisfied, had unaffected respiratory parameters, and had a lower incidence of hoarseness. No difference in handgrip strength or opioid consumption were detected. Superior trunk block was associated with lower worst pain scores on postoperative day 1.

CONCLUSIONS

Compared with the interscalene block, the superior trunk block provides noninferior surgical anesthesia while preserving diaphragmatic function. The superior trunk block may therefore be considered an alternative to traditional interscalene block for shoulder surgery.

摘要

背景

经斜角肌间隙阻滞仍然是肩部手术最常用的麻醉和镇痛方法之一。然而,该阻滞与高发生率的膈肌麻痹相关,因此不能用于肺功能受损的患者。为了解决这个问题,最近的研究已经探索了能够提供镇痛作用而不引起膈肌麻痹的膈神经保护替代方法。然而,没有一种方法能够可靠地证明在没有显著膈神经麻痹风险的情况下提供手术麻醉。上干阻滞的效用尚未得到研究。假设与经斜角肌间隙阻滞相比,上干阻滞将提供非劣效的手术麻醉和镇痛,同时保留膈神经。

方法

这是一项随机对照试验,纳入了 126 例行关节镜日间肩部手术的患者。患者接受上干阻滞(n = 63)或经斜角肌间隙阻滞(n = 63)。主要结局是膈神经麻痹的发生率和恢复室中最严重的疼痛评分。超声用于评估膈神经麻痹。次要结局包括非侵入性测量的呼吸功能参数、阿片类药物消耗量、握力、不良反应和患者满意度。

结果

上干组的膈神经麻痹发生率明显低于经斜角肌间隙组(3/62[4.8%]比 45/63[71.4%];P < 0.001,调整后的优势比为 0.02[95%CI,0.01,0.07]),而恢复室中最严重的疼痛评分则无差异(0[0,2]比 0[0,3];P = 0.951)。上干组的满意度更高,呼吸参数不受影响,且声音嘶哑的发生率较低。握力或阿片类药物消耗量无差异。上干阻滞与术后第 1 天的最严重疼痛评分较低相关。

结论

与经斜角肌间隙阻滞相比,上干阻滞在保留膈肌功能的同时提供非劣效的手术麻醉。因此,上干阻滞可能成为肩部手术中传统经斜角肌间隙阻滞的替代方法。

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