Ahuja Amisha, Ahuja Nitin K
Department of Internal Medicine, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Division of Gastroenterology, University of Pennsylvania, 3400 Civic Center Boulevard, 7 South Pavilion, Philadelphia, PA, 19104, USA.
Curr Gastroenterol Rep. 2019 Jul 10;21(8):39. doi: 10.1007/s11894-019-0707-4.
Popular remedies are of ongoing interest to patients experiencing common esophageal symptoms, particularly as typical pharmacologic interventions have been subject to increased scrutiny. Herein we summarize the available data regarding potential risks and benefits of several such remedies.
With emphasis on reflux and non-cardiac chest pain, research is ongoing into the clinical utility and diverse physiologic mechanisms underlying a variety of complementary and alternative modalities, including dietary manipulation, apple cider vinegar, melatonin, acupuncture, and various herbal products (rikkunshito, STW 5, slippery elm, licorice, and peppermint oil, among others). A substantial gap persists between anecdotal and empirical understandings of the majority of non-pharmacologic remedies for esophageal symptoms. This landscape of popular treatments nevertheless raises several interesting mechanistic hypotheses and compelling opportunities for future research.
常用疗法一直是有常见食管症状患者感兴趣的话题,尤其是随着典型药物干预受到越来越多的审视。在此,我们总结了关于几种此类疗法潜在风险和益处的现有数据。
重点关注反流和非心源性胸痛,针对多种补充和替代疗法(包括饮食调整、苹果醋、褪黑素、针灸以及各种草药产品,如六君子汤、STW 5、滑榆树、甘草和薄荷油等)的临床效用和多样生理机制的研究正在进行。对于大多数治疗食管症状的非药物疗法,传闻与实证理解之间仍存在巨大差距。然而,这种流行治疗的局面提出了几个有趣的机制假说以及未来研究引人注目的机会。