尼日利亚埃努古两个农村社区的乙肝表面抗原血症

Hepatitis B surface antigenemia in two rural communities in Enugu, Nigeria.

作者信息

Meka I A, Onodugo O D, Obienu O, Okite J

机构信息

Department of Chemical Pathology, University of Nigeria Teaching Hospital, Enugu, Nigeria.

Department of Internal Medicine, University of Nigeria Teaching Hospital, Enugu, Nigeria.

出版信息

Niger J Clin Pract. 2019 Jul;22(7):932-935. doi: 10.4103/njcp.njcp_108_18.

DOI:10.4103/njcp.njcp_108_18

PMID:31293257

Abstract

BACKGROUND

Hepatitis B virus infection is endemic in Nigeria, yet few data exist about the extent of infection in rural communities.

OBJECTIVE

To determine seroprevalence of hepatitis B surface antigenemia in two rural communities in Nigeria.

METHODS

A 330-person survey for seroprevalence of hepatitis B surface antigen (HBsAg) was carried out in two rural communities in Enugu State, Nigeria, in January, 2017. All study participants were screened for HBsAg using chromatographic immunoassay. Results: The mean age of participants was 57.2 ± 17.4 years, (range = 10-92 years) with 168 (50.9%) aged 60 years and above. The prevalence of HBsAg was found to be 2.1% with the 18-29 years age group having the highest prevalence.

CONCLUSION

There is need to increase hepatitis B surveillance in rural communities to reduce transmission and institute early treatment.

摘要

背景

乙型肝炎病毒感染在尼日利亚呈地方性流行，但关于农村社区感染程度的数据却很少。

目的

确定尼日利亚两个农村社区乙型肝炎表面抗原血症的血清流行率。

方法

2017年1月，在尼日利亚埃努古州的两个农村社区对330人进行了乙型肝炎表面抗原（HBsAg）血清流行率调查。所有研究参与者均采用色谱免疫分析法进行HBsAg筛查。结果：参与者的平均年龄为57.2±17.4岁（范围=10-92岁），其中168人（50.9%）年龄在60岁及以上。发现HBsAg的流行率为2.1%，18-29岁年龄组的流行率最高。