Nigeria Field Epidemiology and Laboratory Training Programme, Abuja, Nigeria.
Department of Community Medicine, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
BMC Infect Dis. 2020 Mar 6;20(1):194. doi: 10.1186/s12879-020-4863-9.
Hepatitis B virus disease is a potentially life-threatening liver infection and a major global health problem. It causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer. WHO estimated 257 million people are living with hepatitis B virus (HBV) infection and in 2015 alone HBV resulted in to 887,000 deaths globally. We determined the prevalence and associated factors of hepatitis B virus infection among Antenatal Care (ANC) attendees in Gamawa Local Government Area, Bauchi State.
We conducted a descriptive cross-sectional, health facility-based study between March and April 2018. We used systematic random sampling technique to recruit 210 pregnant women aged 15-49 years. With a structured questionnaire, we interviewed the respondents and collected blood sample to test for hepatitis B surface antigen. We calculated frequencies, means, proportions, and tested for associations using Epi Info 7.2 and Microsoft Excel.
The mean age of respondents was 24.5 ± 6.0 years; 112 (53%) of whom were younger than 25 years. All were married, 183 (87%) had no formal education and up to 190 (90%) were employed. Overall, 14 (6.7%) tested positive for HBsAg; women aged ≥35 years had the highest prevalence (10%). None with tertiary education tested positive and women married before 18 years had 13 (6.2%) prevalence.
The prevalence of HBsAg among pregnant women in Gamawa LGA was 6.7% which is quite lower than the national prevalence reported. We recommended improved surveillance of HBV infection and screening of women attending ANC.
乙型肝炎病毒疾病是一种潜在的危及生命的肝脏感染，也是一个重大的全球健康问题。它导致慢性感染，使人们面临肝硬化和肝癌死亡的高风险。世界卫生组织估计，有 2.57 亿人感染乙型肝炎病毒（HBV），仅 2015 年一年，全球就有 88.7 万人死于乙型肝炎病毒。我们确定了包奇州 Gamawa 地方政府区产前护理（ANC）就诊者中乙型肝炎病毒感染的流行率和相关因素。
我们于 2018 年 3 月至 4 月进行了一项描述性横断面、基于卫生机构的研究。我们使用系统随机抽样技术招募了 210 名年龄在 15-49 岁的孕妇。我们使用结构化问卷对受访者进行访谈，并采集血样检测乙型肝炎表面抗原。我们使用 Epi Info 7.2 和 Microsoft Excel 计算频率、平均值、比例，并进行关联检验。
受访者的平均年龄为 24.5±6.0 岁；其中 112 人（53%）年龄小于 25 岁。所有人都已婚，183 人（87%）没有接受过正规教育，多达 190 人（90%）有工作。总的来说，有 14 人（6.7%）乙型肝炎表面抗原检测呈阳性；年龄≥35 岁的女性患病率最高（10%）。没有接受过高等教育的人检测呈阳性，18 岁前结婚的女性患病率为 6.2%（13 人）。
Gamawa LGA 孕妇的 HBsAg 流行率为 6.7%，远低于全国报告的流行率。我们建议加强对乙型肝炎病毒感染的监测和对 ANC 就诊妇女的筛查。
