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机构养老老年人血清总胡萝卜素浓度的决定因素

Determinants of total serum carotene concentrations in institutionalized elderly.

作者信息

Kergoat M J, Leclerc B S, PetitClerc C, Imbach A

机构信息

Department of General Medicine, Centre Hospitalier Côte-des-Neiges, Montreal, Québec, Canada.

出版信息

J Am Geriatr Soc. 1988 May;36(5):430-6. doi: 10.1111/j.1532-5415.1988.tb02382.x.

DOI:10.1111/j.1532-5415.1988.tb02382.x
PMID:3129482
Abstract

The current analysis was designed to examine further the association between total serum carotenoids and a series of preselected variables (dietary intakes, anthropometric parameters, serum cholesterol, vitamin A, transport proteins, and others) using 85 elderly patients. Simple correlation between serum carotene and carotene intake, as estimated by a three-day weighed method, was 0.19 (P = 0.08), which was substantially increased (r = 0.29, P = 0.01) after adjustments for a selected set of variables. Standardized coefficients of multivariate regression indicated that the most important predictors of serum carotene were serum cholesterol (beta = 0.38), total serum proteins (beta = -0.35), and sex (beta = 0.34), followed by carotene intake (beta = 0.28) and midarm circumference (beta = 0.20). These variables accounted for 46% of the variance. Results suggest that serum carotene may be related to protein-energy status in hospitalized elderly, but further investigation should be directed to serum carotene in undernourished elderly. Nevertheless, total serum proteins could be an important factor in any attempt to correlate carotene intake and blood concentration.

摘要

当前的分析旨在使用85名老年患者进一步研究血清总类胡萝卜素与一系列预先选定的变量(饮食摄入量、人体测量参数、血清胆固醇、维生素A、转运蛋白等)之间的关联。通过三日称重法估算,血清胡萝卜素与胡萝卜素摄入量之间的简单相关性为0.19(P = 0.08),在对一组选定变量进行调整后,该相关性大幅增加(r = 0.29,P = 0.01)。多元回归的标准化系数表明,血清胡萝卜素的最重要预测因素是血清胆固醇(β = 0.38)、血清总蛋白(β = -0.35)和性别(β = 0.34),其次是胡萝卜素摄入量(β = 0.28)和上臂围(β = 0.20)。这些变量解释了46%的方差。结果表明,血清胡萝卜素可能与住院老年人的蛋白质 - 能量状况有关,但应进一步研究营养不良老年人的血清胡萝卜素。尽管如此,血清总蛋白可能是任何试图将胡萝卜素摄入量与血液浓度相关联的重要因素。

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Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: a prospective study.老年人蔬菜、水果、β-胡萝卜素、维生素C的摄入量及维生素补充剂与癌症发病率:一项前瞻性研究。
Br J Cancer. 1992 Oct;66(4):673-9. doi: 10.1038/bjc.1992.336.