AlEnazi Abdulaziz, Alhedaithy Riyadh, Alfayez Abdulrhman, Alghonaim Yazeed
Department of Otorhinolaryngology - Head and Neck Surgery , Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University (KFHU), Al Khobar, Saudi Arabia.
Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.
Int J Surg Case Rep. 2019;60:200-203. doi: 10.1016/j.ijscr.2019.05.056. Epub 2019 Jul 9.
Hematologic diseases are rarely present with sudden hearing loss as an initial symptom. Although the precise cause of sudden sensorineural hearing loss has not been identified, several pathophysiological mechanisms have been proposed. However, a variety of hematologic diseases are among the causes of sudden onset deafness. This article represents the first reported case of Hairy cell leukemia (HCL) which presented with acute unilateral profound sensorineural hearing loss as an inital mainfestation.
A 41-year-old man presented with unilateral sudden hearing loss for one day's duration was found to have HCL during a worked up for his hearing loss. The disease worsened, and there was no improvement in his hearing.
Sudden sensorineural hearing loss can rarely be seen as a paraneoplastic occurrence.Very few cases have been reported in the literature. It has been reported as a presenting symptom of leukemia in numerous clinical and histopathological reports concerning the hearing loss in hematologic diseases. Our case is an example of such a rare incidence.
The purpose of this study is to draw physicians' attention to the possible association between acute sensorineural hearing loss to HCL, and to highlights permanent deafness as a complication secondary to HCL. Furthermore, it is important to increase awareness on early diagnosis and treatment that may improve treatment outcomes.
血液系统疾病很少以突发性听力损失作为首发症状。虽然突发性感音神经性听力损失的确切病因尚未明确，但已提出了几种病理生理机制。然而，多种血液系统疾病是突发性耳聋的病因之一。本文报道了首例毛细胞白血病（HCL），其最初表现为急性单侧重度感音神经性听力损失。
一名41岁男性因单侧突发性听力损失一天前来就诊，在对其听力损失进行检查时被诊断为HCL。病情恶化，其听力没有改善。
突发性感音神经性听力损失很少见，可作为副肿瘤现象出现。文献中报道的病例很少。在众多关于血液系统疾病听力损失的临床和组织病理学报告中，突发性感音神经性听力损失已被报道为白血病的一种表现症状。我们的病例就是这种罕见情况的一个例子。
本研究的目的是引起医生对急性感音神经性听力损失与HCL之间可能关联的关注，并强调永久性耳聋是HCL的一种并发症。此外，提高对早期诊断和治疗的认识很重要，这可能会改善治疗效果。
