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1
Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis.吡嗪酰胺对细胞内生长的结核分枝杆菌无效。
Antimicrob Agents Chemother. 1988 Feb;32(2):287. doi: 10.1128/AAC.32.2.287.
2
Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages.克拉霉素和吡嗪酰胺对人巨噬细胞内结核分枝杆菌的协同活性。
Antimicrob Agents Chemother. 1997 Sep;41(9):2035-6. doi: 10.1128/AAC.41.9.2035.
3
[Determination of the sensitivity of tuberculosis bacteria to pyrazinamide using human macrophage culture].[利用人巨噬细胞培养法测定结核杆菌对吡嗪酰胺的敏感性]
Pneumologie. 1990 Feb;44 Suppl 1:460-1.
4
Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages.吡嗪酰胺对培养的人单核细胞衍生巨噬细胞内的结核分枝杆菌无活性。
Int J Tuberc Lung Dis. 2000 Jun;4(6):491-5.
5
Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system.吡嗪酰胺和吡嗪酸在培养的人巨噬细胞及BACTEC系统中对结核杆菌的活性。
J Infect Dis. 1990 Jul;162(1):201-7. doi: 10.1093/infdis/162.1.201.
6
Inhibition of M. tuberculosis in vitro in monocytes and in mice by aminomethylene pyrazinamide analogs.
Tuberculosis (Edinb). 2008 Sep;88(5):410-9. doi: 10.1016/j.tube.2008.06.001.
7
Pyrazinamidase activity of Mycobacterium tuberculosis--a test of sensitivity to pyrazinamide.
Tubercle. 1987 Sep;68(3):221-4. doi: 10.1016/0041-3879(87)90058-4.
8
Pyrazinamide sterilizing activity in vitro against semidormant Mycobacterium tuberculosis bacterial populations.吡嗪酰胺对半休眠结核分枝杆菌菌群的体外杀菌活性。
Am Rev Respir Dis. 1992 May;145(5):1223-5. doi: 10.1164/ajrccm/145.5.1223.
9
Pyrazinamide Is Active against Mycobacterium tuberculosis Cultures at Neutral pH and Low Temperature.吡嗪酰胺在中性pH值和低温条件下对结核分枝杆菌培养物具有活性。
Antimicrob Agents Chemother. 2016 Jul 22;60(8):4956-60. doi: 10.1128/AAC.00654-16. Print 2016 Aug.
10
Susceptibility of Mycobacterium tuberculosis to pyrazinamide and its relationship to pyrazinamidase activity.结核分枝杆菌对吡嗪酰胺的敏感性及其与吡嗪酰胺酶活性的关系。
Antimicrob Agents Chemother. 1983 Oct;24(4):600-1. doi: 10.1128/AAC.24.4.600.

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1
Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide.抑制宿主 PARP1 有助于吡嗪酰胺的抗炎和抗结核活性。
Nat Commun. 2023 Dec 9;14(1):8161. doi: 10.1038/s41467-023-43937-1.
2
Impact of the host environment on the antitubercular action of pyrazinamide.宿主环境对吡嗪酰胺抗结核作用的影响。
EBioMedicine. 2019 Nov;49:374-380. doi: 10.1016/j.ebiom.2019.10.014. Epub 2019 Oct 25.
3
Targeting Phenotypically Tolerant Mycobacterium tuberculosis.针对表型耐受的结核分枝杆菌。
Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0031-2016.
4
The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.依从性和再次治疗在耐多药结核病初发中的作用
PLoS Comput Biol. 2016 Mar 11;12(3):e1004749. doi: 10.1371/journal.pcbi.1004749. eCollection 2016 Mar.
5
High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.高内涵筛选技术结合人肉芽肿模型作为评估抗结核药物活性的新方法。
Antimicrob Agents Chemother. 2015 Jan;59(1):693-7. doi: 10.1128/AAC.03705-14. Epub 2014 Oct 27.
6
Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection.针对结核分枝杆菌感染中吡嗪酰胺的宿主靶向活性。
PLoS One. 2013 Aug 28;8(8):e74082. doi: 10.1371/journal.pone.0074082. eCollection 2013.
7
Extracellular and intracellular activities of clarithromycin used alone and in association with ethambutol and rifampin against Mycobacterium avium complex.克拉霉素单独使用以及与乙胺丁醇和利福平联合使用时对鸟分枝杆菌复合群的细胞外和细胞内活性。
Antimicrob Agents Chemother. 1991 Mar;35(3):462-70. doi: 10.1128/AAC.35.3.462.

本文引用的文献

1
The intracellular activation of pyrazinamide and nicotinamide.吡嗪酰胺和烟酰胺的细胞内激活作用。
Am Rev Tuberc. 1956 Nov;74(5):718-28. doi: 10.1164/artpd.1956.74.5.718.
2
Determination of drug susceptibility of mycobacteria to pyrazinamide in 7H10 agar.
Am Rev Respir Dis. 1967 Nov;96(5):1072-5. doi: 10.1164/arrd.1967.96.5.1072.
3
The penetration of rifampicin, pyrazinamide, and pyrazinoic acid into mouse macrophages.
Am Rev Respir Dis. 1985 Dec;132(6):1268-73. doi: 10.1164/arrd.1985.132.6.1268.
4
Killing of macrophage-ingested mycobacteria by rifampicin, pyrazinamide, and pyrazinoic acid alone and in combination.利福平、吡嗪酰胺和吡嗪酸单独及联合使用对巨噬细胞吞噬的分枝杆菌的杀灭作用。
Am Rev Respir Dis. 1985 Dec;132(6):1274-7. doi: 10.1164/arrd.1985.132.6.1274.
5
Structure of the cell envelope of Mycobacterium avium.鸟分枝杆菌细胞包膜的结构
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Apr;264(1-2):49-66. doi: 10.1016/s0176-6724(87)80124-4.
6
Inhibition by pyrazinamide of tubercle bacilli within cultured human macrophages.吡嗪酰胺对培养的人巨噬细胞内结核杆菌的抑制作用。
Am Rev Respir Dis. 1986 Nov;134(5):1052-5. doi: 10.1164/arrd.1986.134.5.1052.

Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis.

作者信息

Rastogi N, Potar M C, David H L

出版信息

Antimicrob Agents Chemother. 1988 Feb;32(2):287. doi: 10.1128/AAC.32.2.287.

DOI:10.1128/AAC.32.2.287
PMID:3129990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172157/
Abstract
摘要